Mortada Hatan, Murrad Khalid, Alkadi Danah, AlAbdali Ahmed, Alhamzah Hamzah Ali, Kattan Abdullah
From Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia.
Department of Plastic Surgery and Burn Unit, King Saud Medical City, Riyadh, Saudi Arabia.
Plast Reconstr Surg Glob Open. 2023 Sep 21;11(9):e5277. doi: 10.1097/GOX.0000000000005277. eCollection 2023 Sep.
Silicone liquid (polydimethylsiloxane) is an inert material commonly used for cosmetic purposes. A combination of both systematic and local devastating complications can cause end-organ toxicity and multi-organ dysfunction. In this article, we examine the literature and present a case of a patient who presented with lower extremity filler migration and granuloma formation 11 years post gluteal silicone injection. A 31-year-old woman who had received a gluteal silicone injection 11 years ago was experiencing painful erythema, progressive fibrosis, and swelling as the result of the injection. The patient was diagnosed with postfiller autoimmune syndrome. Multiple surgical interventions were conducted to remove the permanent filler from her left knee. As a result of multiple surgical sessions, the patient has been managed successfully with no relapses. This case demonstrated complications of an unusual silicone injection technique for gluteal augmentation. Despite silicone being considered inert, complications can arise years after injection, necessitating extensive medical intervention. This case also raises questions regarding the systemic effects of silicone fillers, warranting further research. Through this report, we aimed to enhance awareness and management of similar future cases.
硅酮液体（聚二甲基硅氧烷）是一种常用于美容目的的惰性材料。系统性和局部毁灭性并发症的综合作用可导致终末器官毒性和多器官功能障碍。在本文中，我们查阅了文献，并呈现了一例患者的病例，该患者在臀部注射硅酮11年后出现下肢填充剂迁移和肉芽肿形成。一名11年前接受过臀部硅酮注射的31岁女性，因注射出现疼痛性红斑、进行性纤维化和肿胀。该患者被诊断为填充剂后自身免疫综合征。进行了多次手术干预以从她的左膝取出永久性填充剂。经过多次手术，患者已成功治愈且未复发。该病例展示了一种不寻常的臀部增大硅酮注射技术的并发症。尽管硅酮被认为是惰性的，但并发症可能在注射数年之后出现，需要进行广泛的医学干预。该病例还引发了关于硅酮填充剂全身影响的问题，值得进一步研究。通过本报告，我们旨在提高对未来类似病例的认识和管理水平。
