Thompson Zoe, Hothi Harry, Brillantes Jacqueline, Khoshbin Amir, Atrey Amit
University of Toronto, Toronto, Canada.
The Royal National Orthopaedic Hospital, Stanmore, UK.
Arthroplast Today. 2023 Sep 19;23:101184. doi: 10.1016/j.artd.2023.101184. eCollection 2023 Oct.
Acrylic-based bone cement (polymethyl methacrylate [PMMA]) is a material commonly used in orthopaedic surgeries; however, during PMMA polymerization, a highly exothermic reaction occurs. The heat released in polymerization can damage nearby materials including poorly heat-resistant cross-linked polyethylene (XLPE). Both PMMA and XLPE are used in total hip arthroplasty and could interact during femoral stem fixation. We sought to determine if the exothermic polymerization of PMMA could alter the surface characteristics of XLPE acetabular liners.
Six XLPE liners were assigned to one of 4 experimental categories with varying volumes of PMMA applied in a manner that mimicked how the 2 materials would come into contact intraoperatively. Measurements were taken both pre- and post-intervention using a coordinate measuring machine for geometric and gravimetric analysis. Light microscopy was conducted postintervention to examine the surface for damage.
Coordinate measuring machine measurements showed minimal gross deformation in all 6 liners, but there were isolated surface deposits in 4 of 6 liners. The average maximal surface deviations, when compared to the control, for liners exposed to 1 cc of cement, 2 cc of cement, or 1 cc of cement with a femoral head implant attached were 26.6 μm, 77.2 μm, and 26.4 μm, respectively. All but one liner showed an increase in volume following intervention when compared to the control. Subtle scratches were identified using light microscopy on all 6 liners.
XLPE shows areas of isolated surface deformation in a dose-dependent manner but with minimal gross deformation after interacting with highly exothermic PMMA.
丙烯酸基骨水泥(聚甲基丙烯酸甲酯[PMMA])是骨科手术中常用的材料;然而,在PMMA聚合过程中会发生高度放热反应。聚合过程中释放的热量会损坏附近的材料,包括耐热性差的交联聚乙烯(XLPE)。PMMA和XLPE都用于全髋关节置换术,并且在股骨柄固定过程中可能相互作用。我们试图确定PMMA的放热聚合是否会改变XLPE髋臼衬垫的表面特性。
将六个XLPE衬垫分配到4个实验类别中的一个,以模拟这两种材料在术中接触的方式施加不同体积的PMMA。在干预前后使用坐标测量机进行测量,以进行几何和重量分析。干预后进行光学显微镜检查以检查表面是否有损伤。
坐标测量机测量显示所有6个衬垫的总体变形最小,但6个衬垫中有4个存在孤立的表面沉积物。与对照组相比,暴露于1立方厘米骨水泥、2立方厘米骨水泥或附着有股骨头植入物的1立方厘米骨水泥的衬垫的平均最大表面偏差分别为26.6微米、77.2微米和26.4微米。与对照组相比,除一个衬垫外,所有衬垫在干预后体积均增加。使用光学显微镜在所有6个衬垫上均发现了细微划痕。
XLPE与高度放热的PMMA相互作用后,呈现出剂量依赖性的孤立表面变形区域,但总体变形最小。