Departamento de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Madrid, Spain; Centro Internacional de Oftalmología Avanzada, Madrid, Spain.
Departamento de Oftalmología, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria (IdISSC), Madrid, Spain.
Arch Soc Esp Oftalmol (Engl Ed). 2023 Nov;98(11):633-639. doi: 10.1016/j.oftale.2023.07.007. Epub 2023 Sep 23.
To assess the impact on the quality of life (QoL) among different retinal diseases such as diabetic macular edema (DME), retinal vein occlusion (RVO), pathologic myopia (PM), neovascular age-related macular degeneration (nAMD) and central serous chorioretinopathy (CSC).
A cross-sectional study was carried out in 241 patients, affected by DME (n=44), RVO (n=41), PM (n=34) and nAMD (n=85) receiving intravitreal injections due to the presence of macular edema or choroidal neovascularization. The CSC patients included (n=37) were candidates for laser treatment. The patients included completed the National Eye Visual Functioning Questioning-25 (NEI VFQ-25). Best eye visual acuity (BEVA) was recorded using the Early Treatment Diabetic Retinopathy Study (ETDRS) scale.
There were significant differences between subgroups for all the domains, except for the general vision in which all scores among diseases ranged from 40.7 to 45.2 out of 100 (P=.436), despite the difference in BEVA (CSC: 86.3±11.9; RVO: 78.5±15.5, DME: 73.3±15.2, nAMD: 72.9±12.6 and PM: 68.5±18.1 letters respectively; P<.001). The lowest VFQ-25 total score was observed in the PM patients (52.1±20.9), followed by nAMD (55.3±20.8), RVO (65.0±22.3), DME (68.6±21.0) and CSC (70.9±16.2). The DME group reported the worst score for general health (38.9±21.4). Mental health and role difficulties were lowest for PM (48.2±28.8 and 48.2±31.9, P<.007).
This study reveals the differences in the QoL among DME, RVO, nAMD, PM and CSC, describing the different repercussions that they can suffer, observing a higher impact in PM and nAMD.
评估不同视网膜疾病（如糖尿病性黄斑水肿[DME]、视网膜静脉阻塞[RVO]、病理性近视[PM]、新生血管性年龄相关性黄斑变性[nAMD]和中心性浆液性脉络膜视网膜病变[CSC]）对生活质量（QoL）的影响。
对 241 例接受玻璃体腔内注射以治疗黄斑水肿或脉络膜新生血管的患者进行了一项横断面研究，其中 DME（n=44）、RVO（n=41）、PM（n=34）和 nAMD（n=85）患者存在视网膜疾病，CSC 患者（n=37）为激光治疗的候选者。患者完成了国家眼科视觉功能调查问卷-25（NEI VFQ-25）。最佳眼视力（BEVA）采用早期糖尿病视网膜病变研究（ETDRS）量表记录。
除一般视力外，所有疾病的各亚组在所有领域的得分均存在显著差异，而一般视力的所有疾病的得分均在 100 分中的 40.7 至 45.2 之间（P=.436），尽管 BEVA 有所不同（CSC：86.3±11.9；RVO：78.5±15.5，DME：73.3±15.2，nAMD：72.9±12.6，PM：68.5±18.1 个字母；P<.001）。PM 患者的 VFQ-25 总分最低（52.1±20.9），其次是 nAMD（55.3±20.8）、RVO（65.0±22.3）、DME（68.6±21.0）和 CSC（70.9±16.2）。DME 组的一般健康评分最差（38.9±21.4）。PM 患者的心理健康和角色困难评分最低（48.2±28.8 和 48.2±31.9，P<.007）。
本研究揭示了 DME、RVO、nAMD、PM 和 CSC 之间 QoL 的差异，描述了它们可能遭受的不同影响，观察到 PM 和 nAMD 的影响更大。
