Department of Anesthesiology, Perioperative and Pain Medicine, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China (mainland).
Department of Pharmacology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, China (mainland).
Med Sci Monit. 2023 Sep 26;29:e940916. doi: 10.12659/MSM.940916.
BACKGROUND The purpose of this study was to compare the effectiveness and safety of the MedAn videolaryngoscope with the Nishikawa blade (MedAn) vs the UE videolaryngoscope (UE) for intubation with a left-sided double-lumen endobronchial tube (LDLT) in patients with normal airways. MATERIAL AND METHODS We randomly categorized 106 patients scheduled to undergo elective thoracic surgery with LDLT for one-lung ventilation into 2 groups: the UE group (Group UE) and the MedAn group (Group MedAn), using the MedAn or UE for LDLT intubation. The primary outcome was time to successful intubation. The Cormack-Lehane classification of laryngeal view was the key secondary outcome. Other secondary outcomes included first-attempt and overall intubation success rates, laryngoscopy time, LDLT placement time, operators' subjective evaluation of videolaryngoscopes, hemodynamic changes during videolaryngoscopic intubation, and adverse outcomes. RESULTS The time to successful intubation and LDLT placement time of Group MedAn were 42.0 (32.35, 47.0) s and 23.0 (18.0, 26.0) s, and it was shorter than in Group UE (median, 42 s vs 49 s, 23 s vs 30 s, P<0.001). Group MedAn had a better laryngeal view (P=0.03) and less subglottic/tracheal mucosal injury (P<0.001) than Group UE. Moreover, the operators' subjective grading of ease of laryngoscopy, quality of view, and ease of LDLT placement were higher in Group MedAn than in Group UE (P<0.05). CONCLUSIONS Compared with the UE, the MedAn could reduce the intubation time and provide a better laryngeal view and sufficient intubation space for safer LDLT intubation in patients with normal airways.
本研究旨在比较 MedAn 视频喉镜(MedAn)与 UE 视频喉镜(UE)在气道正常的患者中使用左侧双腔支气管内导管(LDLT)插管的效果和安全性。
我们将 106 例行择期胸外科手术并使用 LDLT 行单肺通气的患者随机分为 2 组:UE 组(UE 组)和 MedAn 组(MedAn 组),分别使用 MedAn 或 UE 进行 LDLT 插管。主要结局是成功插管的时间。喉镜片视图的 Cormack-Lehane 分级是关键次要结局。其他次要结局包括首次尝试和总体插管成功率、喉镜检查时间、LDLT 放置时间、操作者对视频喉镜的主观评价、视频喉镜插管期间的血流动力学变化以及不良结局。
MedAn 组的插管时间和 LDLT 放置时间分别为 42.0(32.35,47.0)s 和 23.0(18.0,26.0)s,明显短于 UE 组(中位数,42 s 比 49 s,23 s 比 30 s,P<0.001)。MedAn 组的喉镜片视图更好(P=0.03),且发生声门下/气管黏膜损伤的比例更低(P<0.001)。此外,MedAn 组的操作者对喉镜检查的易操作性、视野质量和 LDLT 放置的易操作性的主观评分均高于 UE 组(P<0.05)。
与 UE 相比,MedAn 可缩短插管时间,并为气道正常的患者提供更好的喉部视野和充足的插管空间,从而更安全地进行 LDLT 插管。