Lungu G, Zosin I, Miloş A, Vlad A G, Peev T, Moş E, Stoicoiu M
Endocrinologie. 1986 Jul-Sep;24(3):197-201.
We studied the calcium tolerance on 59 subjects with tetania latenta. The calcium tolerance was tested by induced hypercalcemia (Klotz's test). In 12 cases the dynamic changes of serum magnesium were also investigated during the same test. Eight cases exhibited a normal tolerance and 51 exhibit an abnormal response, calcemia remaining at a high value after 4 hours of the test. The magnesium values remained low when finishing the test (p less than 0.001). It was concluded that 86 per cent of the subjects having tetania latenta and exhibiting an increase of calcium tolerance had a possible calcitonin deficiency. The significance of the magnesium decrease remains unclear. These phenomena have not been observed in Graves' disease and in the Turner's syndrome.
我们对59例隐匿性手足搐搦症患者进行了钙耐受性研究。通过诱导高钙血症(克洛茨试验)来测试钙耐受性。在同一试验中,还对12例患者血清镁的动态变化进行了研究。8例表现出正常耐受性,51例表现出异常反应,试验4小时后血钙仍维持在较高水平。试验结束时镁值仍较低(p<0.001)。得出的结论是,86%隐匿性手足搐搦症且钙耐受性增加的患者可能存在降钙素缺乏。镁降低的意义尚不清楚。这些现象在格雷夫斯病和特纳综合征中未观察到。