Shmunis School of Biomedicine and Cancer Research, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel.
Department of Chemistry, Ben Gurion University of the Negev, 84105 Beer Sheva, Israel.
Chem Commun (Camb). 2023 Oct 12;59(82):12298-12301. doi: 10.1039/d3cc03945e.
Here, we utilized designed condensates formed by liquid-liquid phase separation (LLPS) of cationic and aromatic peptide to sequester tyrosine-based carbon dots (C-dots). The C-dots fluorescence is quenched and retrieved upon partitioning and release from condensates, allowing a spatial regulation of C-dots fluorescence which can be utilized for biosensing applications.
在这里，我们利用通过阳离子和芳香族肽的液-液相分离（LLPS）形成的设计冷凝物来隔离基于酪氨酸的碳点（C-点）。C-点荧光在从冷凝物分配和释放时被猝灭和恢复，从而允许对 C-点荧光进行空间调节，可将其用于生物传感应用。
