Alaithan Tajah M, Alharbi Lama K, Aldusaymani Saba M, Al Khuwaitir Tarig S
Medicine and Surgery, Al Maarefa University, Riyadh, SAU.
Internal Medicine, King Saud Medical City, Riyadh , SAU.
Cureus. 2023 Aug 25;15(8):e44093. doi: 10.7759/cureus.44093. eCollection 2023 Aug.
Wernicke's encephalopathy (WE) is an acute neuropsychiatric emergency due to thiamine deficiency. This report includes a case of a young pregnant female in her second trimester (17th weeks) complaining of hyperemesis gravidarum, who, due to excessive vomiting, developed severe vitamin B1 deficiency, leading to WE and Korsakoff's psychosis. The typical triad of confusion, ocular signs, and ataxia is fundamental for the diagnosis of WE, yet not all cases present with the entire triad; however, our patient presented with all the symptoms. Replacement of thiamine, which is a crucial vitamin that plays an important role in the integrity of the nervous system, is the first step in the management of WE.
韦尼克脑病(WE)是一种因硫胺素缺乏引起的急性神经精神急症。本报告包含一例孕中期(第17周)年轻孕妇的病例,该孕妇主诉妊娠剧吐,由于过度呕吐,导致严重维生素B1缺乏,进而引发韦尼克脑病和科萨科夫精神病。意识模糊、眼部体征和共济失调这一典型三联征是诊断韦尼克脑病的根本依据,但并非所有病例都出现完整的三联征;然而,我们的患者出现了所有这些症状。硫胺素替代疗法是韦尼克脑病治疗的第一步,硫胺素是一种对神经系统完整性起重要作用的关键维生素。