Ahmed Shakeel, Ahmed Dania, Abo Salah Salem, Mathew Joe, Yousaf Zohaib
Pulmonology, Hamad Medical Corporation, Doha, QAT.
Medicine, College of Physicians and Surgeons Pakistan, Karachi, PAK.
Cureus. 2020 Aug 25;12(8):e10012. doi: 10.7759/cureus.10012.
Wernicke's encephalopathy (WE) is a potentially reversible yet severe neurological manifestation caused by thiamine (vitamin B1) deficiency. It is commonly associated with heavy alcohol consumption. Other rare causes include severe and prolonged vomiting, starvation, and prolonged intravenous feeding. WE patients usually present with the triad of ocular signs, ataxia, and confusion. In non-alcoholic patients, the full classic triad develops in 10-16% of cases. Characteristic MRI findings and clinical response to thiamine confirm the diagnosis. In this report, we present a case of WE in the setting of transient gestational hyperthyroidism and hyperemesis gravidarum (HG).
韦尼克脑病(WE)是一种由硫胺素(维生素B1)缺乏引起的潜在可逆但严重的神经学表现。它通常与大量饮酒有关。其他罕见原因包括严重且持续的呕吐、饥饿和长期静脉内喂养。WE患者通常表现为眼征、共济失调和意识模糊三联征。在非酒精性患者中,10% - 16%的病例会出现完整的典型三联征。特征性的MRI表现和对硫胺素的临床反应可确诊。在本报告中,我们介绍了一例发生在短暂性妊娠甲状腺功能亢进症和妊娠剧吐(HG)背景下的WE病例。