Kantor Sandeep, Prakash Sadanandan, Chandwani Juhi, Gokhale Antara, Sarma Kalpana, Albahrani Maher J
Division of Anesthesia and Critical Care, Royal Hospital, Muscat, Oman.
Indian J Crit Care Med. 2014 Mar;18(3):164-6. doi: 10.4103/0972-5229.128706.
Wernicke's encephalopathy (WE) is a potentially reversible yet serious neurological manifestation caused by vitamin B1(thiamine) deficiency. It is commonly associated with heavy alcohol consumption. Other clinical associations are with hyperemesis gravidarum (HG), starvation, and prolonged intravenous feeding. Most patients present with the triad of ocular signs, ataxia, and confusion. It can be associated with life-threatening complication like central pontine myelinolysis (CPM). We report two cases of WE following HG, with two different outcomes.
韦尼克脑病(WE)是一种由维生素B1(硫胺素)缺乏引起的潜在可逆但严重的神经学表现。它通常与大量饮酒有关。其他临床关联包括妊娠剧吐(HG)、饥饿和长期静脉营养。大多数患者表现为眼征、共济失调和意识模糊三联征。它可能与危及生命的并发症如中枢桥脑髓鞘溶解症(CPM)有关。我们报告了两例HG后发生的WE病例,结果不同。