Ribas Marcelo Romanovitch, Schneider Fábio Kurt, Ribas Danieli Isabel Romanovitch, Lass André Domingues, Badicu Georgian, Bassan Júlio Cesar
Postgraduate Program in Electrical Engineering and Industrial Informatics, Universidade Tecnológica Federal do Paraná, Curitiba 80230901, Brazil.
Human Genetics Laboratory, Centro Universitário Autônomo do Brasil (UniBrasil), Curitiba 82821020, Brazil.
Eur J Investig Health Psychol Educ. 2023 Sep 10;13(9):1751-1761. doi: 10.3390/ejihpe13090127.
Although the studied polymorphisms affect muscular proteins, aerobic adaptations, and recovery, their influence on the anthropometric variables and performance in ultramarathon runners is still poorly understood. This study aimed to determine the influence of , , and polymorphisms on the changes in the anthropometric variables and running time of 105 km mountain runners, in which 22 male Brazilian elite athletes (35.9 ± 6.5 years) were evaluated. Genotyping of the (RR, RX, and XX), (DD, ID, and II), and (AA, AG, and GG) polymorphisms was performed using the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) technique with DNA extracted from saliva. Body composition was determined via bioimpedance. Pre- and post-race weight differences were observed on athletes with the AA genotype (77.1 ± 5.9 kg; 74.6 ± 5.6 kg) compared with those with the AG genotype (74.5 ± 8.0 kg; 68 ± 5.1 kg) ( = 0.02; = 0.02). The RR genotype showed a correlation between BMI and running time (R = 0.97; = 0.004). The genotype II showed a correlation with % fat and fat mass concerning running time (R = 0.91; = 0.003; R = 0.99; < 0.0001). The AA genotype was associated with post-race weight and lean mass loss, while the RR genotype correlated with BMI, and the genotype II correlated with % body fat and fat mass in relation to times in the 105 km mountain ultramarathon.
尽管所研究的多态性会影响肌肉蛋白、有氧适应能力和恢复能力，但它们对超马拉松运动员人体测量学变量和运动表现的影响仍知之甚少。本研究旨在确定[具体基因名称1]、[具体基因名称2]和[具体基因名称3]多态性对105公里山地跑运动员人体测量学变量变化和跑步时间的影响，对22名巴西男性精英运动员（35.9±6.5岁）进行了评估。使用聚合酶链反应-限制性片段长度多态性（PCR-RFLP）技术，从唾液中提取DNA，对[具体基因名称1]（RR、RX和XX）、[具体基因名称2]（DD、ID和II）和[具体基因名称3]（AA、AG和GG）多态性进行基因分型。通过生物电阻抗法测定身体成分。观察到AA基因型运动员（77.1±5.9千克；74.6±5.6千克）与AG基因型运动员（74.5±8.0千克；68±5.1千克）相比，赛前和赛后体重差异（P = 0.02；P = 0.02）。RR基因型显示BMI与跑步时间之间存在相关性（R = 0.97；P = 0.004）。II基因型显示与%脂肪和脂肪量有关的跑步时间存在相关性（R = 0.91；P = 0.003；R = 0.99；P < 0.0001）。AA基因型与赛后体重和去脂体重减轻有关，而RR基因型与BMI相关，II基因型与105公里山地超马拉松比赛时间相关的%体脂和脂肪量相关。
