Mihu Carina, Popescu Codruța Alina, Neag Maria Adriana, Bocşan Ioana Corina, Melincovici Carmen Stanca, Baican Adrian Lucian, Năsui Bogdana Adriana, Buzoianu Anca-Dana
Department of Pharmacology, Toxicology and Clinical Pharmacology, Iuliu Haţieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Department of Human Sciences, Iuliu Haţieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
J Clin Med. 2023 Sep 16;12(18):6000. doi: 10.3390/jcm12186000.
Psoriasis is one of the most frequent chronic inflammatory skin diseases and has a negative impact on the interpersonal relationship and psychosocial well-being. The aims of this study were to examine the effects of intensity of pruritus on quality of life and depression, to investigate the relationship between anger, self-esteem, and depression, and to compare patients with early and late onset of psoriasis. As our study was carried out during the COVID-19 pandemic, we aimed also to investigate the safety concerns and anxiety related to COVID-19 in psoriasis patients.
This cross-sectional study included 137 patients diagnosed with plaque psoriasis. The patients were classified as early-onset (age < 30 years) and late-onset psoriasis (age ≥ 30 years). Duration of disease, pruritus scores, and socio-demographic characteristics were recorded. Measures included the State-Trait Anger Expression Inventory (STAXI), Rosenberg Self-Esteem Scale, Beck Depression Inventory (BDI-II), Psoriasis Disability Index (PDI), and Fear and anxiety in relationship with COVID-19 Scale were used for determining anger, anger expression style, self-esteem, depression, anxiety, and quality of life.
The psoriasis patients had a lower score for self-esteem than the normative data from the Romanian general population. The average scores for state anger and trait anger are similar to the normative data from the Romanian general population, but the scores for anger-in and anger-out are higher. Patients with early onset had higher depression scores and lower quality of life. Self-esteem correlates negatively with depression, anger, severity of disability due to psoriasis, number of affected areas, and duration of disease. Lower level of self-esteem led to increased anger.
Reduced self-esteem, increased anger levels, and depression are present in psoriasis patients. The effective treatment of psoriasis must, therefore, consist of a multidisciplinary approach, in which the personalized treatment of the skin condition is as important as the adjuvant therapies that reduce the patients' stress level.
银屑病是最常见的慢性炎症性皮肤病之一，对人际关系和心理社会幸福感有负面影响。本研究的目的是探讨瘙痒强度对生活质量和抑郁的影响，调查愤怒、自尊与抑郁之间的关系，并比较早发型和晚发型银屑病患者。由于我们的研究是在新冠疫情期间进行的，我们还旨在调查银屑病患者对新冠病毒的安全担忧和焦虑。
这项横断面研究纳入了137例被诊断为斑块状银屑病的患者。患者被分为早发型（年龄<30岁）和晚发型银屑病（年龄≥30岁）。记录疾病持续时间、瘙痒评分和社会人口学特征。使用状态-特质愤怒表达量表（STAXI）、罗森伯格自尊量表、贝克抑郁量表（BDI-II）、银屑病残疾指数（PDI）以及与新冠病毒相关的恐惧和焦虑量表来确定愤怒、愤怒表达风格、自尊、抑郁、焦虑和生活质量。
银屑病患者的自尊得分低于罗马尼亚普通人群的标准数据。状态愤怒和特质愤怒的平均得分与罗马尼亚普通人群的标准数据相似，但愤怒内向和愤怒外向的得分更高。早发型患者的抑郁得分更高，生活质量更低。自尊与抑郁、愤怒、银屑病导致的残疾严重程度、受累面积数量和疾病持续时间呈负相关。自尊水平较低导致愤怒增加。
银屑病患者存在自尊降低、愤怒水平升高和抑郁的情况。因此，银屑病的有效治疗必须采用多学科方法，其中皮肤疾病的个性化治疗与降低患者压力水平的辅助治疗同样重要。
