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Int J Womens Dermatol. 2017 Sep 4;4(2):91-94. doi: 10.1016/j.ijwd.2017.07.001. eCollection 2018 Jun.
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Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases.苔藓样糠疹和额部纤维性脱发作为上皮干细胞疾病的模型。
Trends Mol Med. 2018 May;24(5):435-448. doi: 10.1016/j.molmed.2018.03.007. Epub 2018 Apr 13.
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Therapeutic management of classic lichen planopilaris: a systematic review.经典扁平苔藓样毛发角化病的治疗管理:一项系统评价。
Clin Cosmet Investig Dermatol. 2018 Feb 27;11:91-102. doi: 10.2147/CCID.S137870. eCollection 2018.
4
Health-Related Quality of Life in Patients With Frontal Fibrosing Alopecia.患有额部纤维性脱发的患者的健康相关生活质量。
JAMA Dermatol. 2018 Apr 1;154(4):479-480. doi: 10.1001/jamadermatol.2017.6330.
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Pattern and prevalence of psychiatric disorders among patients attending dermatology OPD.皮肤科门诊患者精神障碍的模式和流行情况。
Asian J Psychiatr. 2017 Oct;29:85-88. doi: 10.1016/j.ajp.2017.04.018. Epub 2017 Apr 28.
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Update on lichen planus and its clinical variants.扁平苔藓及其临床变体的最新进展。
Int J Womens Dermatol. 2015 Sep 16;1(3):140-149. doi: 10.1016/j.ijwd.2015.04.001. eCollection 2015 Aug.
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Quality of life assessment in patients with alopecia areata and androgenetic alopecia in the People's Republic of China.中华人民共和国斑秃和雄激素性脱发患者的生活质量评估
Patient Prefer Adherence. 2017 Jan 27;11:151-155. doi: 10.2147/PPA.S121218. eCollection 2017.
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Lichen planopilaris epidemiology: a retrospective study of 80 cases.扁平苔藓样毛发角化病的流行病学:一项对80例病例的回顾性研究。
An Bras Dermatol. 2015 Sep-Oct;90(5):666-70. doi: 10.1590/abd1806-4841.20153923.
9
Twelve-month prevalence and correlates of psychiatric disorders in Iran: the Iranian Mental Health Survey, 2011.伊朗精神障碍的12个月患病率及其相关因素:2011年伊朗心理健康调查
Arch Iran Med. 2015 Feb;18(2):76-84.
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Quality of life and psychosocial impact of scarring and non-scarring alopecia in women.女性瘢痕性和非瘢痕性脱发对生活质量及心理社会的影响
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基于皮肤病生活质量指数和一般健康问卷-28的扁平苔藓性毛发角化病患者的生活质量和心理健康状况

Quality of life and mental health status in patients with lichen planopilaris based on Dermatology Life Quality Index and General Health Questionnaire-28 questionnaires.

作者信息

Nasimi Maryam, Ahangari Narges, Lajevardi Vahide, Mahmoudi Hamidreza, Ghodsi Seyedeh Zahra, Etesami Ifa

机构信息

Department Of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Int J Womens Dermatol. 2020 Sep 17;6(5):399-403. doi: 10.1016/j.ijwd.2020.09.005. eCollection 2020 Dec.

DOI:10.1016/j.ijwd.2020.09.005
PMID:33898707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8060658/
Abstract

BACKGROUND

Lichen planopilaris (LPP) is a relatively uncommon inflammatory skin condition that causes permanent hair loss. Irreversible hair loss can have a significant psychosocial and psychological impact on patients' lives. Limited studies have assessed the psychological status of patients suffering from LPP, and to our knowledge, none have evaluated patients with LPP as a separate group in this regard.

OBJECTIVE

This study aimed to assess the quality of life (QoL) and general health of patients with LPP using the Dermatology Life Quality Index (DLQI) questionnaire and General Health Questionnaire-28 (GHQ-28), respectively.

METHODS

Our study employed a cross-sectional design. In total, 41 patients with LPP attending the follow-up skin clinic at the Razi Hospital in Tehran, Iran were asked to complete the DLQI and GHQ-28. Furthermore, selected demographic information was obtained from patients to evaluate their association with general health and QoL.

RESULTS

Forty-one patients (14 men and 27 women) with a mean age of 44.02 ± 10.8 years completed both questionnaires. QoL was affected moderately to extremely in 70.7% of patients. Also, 26 patients (63.4%) were at risk for psychological disorders. Lower QoL was reported by patients age <45 years ( < .05). Both QoL and general health had a negative relation with the disease activity index ( < .05), but were not affected by sex, marital status, education level, treatment type, presence of mucous lesions, and disease duration.

CONCLUSION

LPP significantly affects patients' QoL and general health. Dermatologists should address these issues in patients with LPP alongside treating physical symptoms.

摘要

背景

扁平苔藓性毛囊炎(LPP)是一种相对罕见的炎症性皮肤病,可导致永久性脱发。不可逆的脱发会对患者的生活产生重大的社会心理影响。有限的研究评估了LPP患者的心理状况,据我们所知,尚无研究将LPP患者作为一个单独的群体在这方面进行评估。

目的

本研究旨在分别使用皮肤病生活质量指数(DLQI)问卷和一般健康问卷-28(GHQ-28)评估LPP患者的生活质量(QoL)和总体健康状况。

方法

我们的研究采用横断面设计。总共邀请了41名在伊朗德黑兰拉齐医院皮肤科门诊接受随访的LPP患者完成DLQI和GHQ-28。此外,从患者那里获取了选定的人口统计学信息,以评估它们与总体健康和生活质量的关联。

结果

41名患者(14名男性和27名女性)完成了两份问卷,平均年龄为44.02±10.8岁。70.7%的患者生活质量受到中度至极度影响。此外,26名患者(63.4%)有心理障碍风险。年龄<45岁的患者报告的生活质量较低(<0.05)。生活质量和总体健康状况均与疾病活动指数呈负相关(<0.05),但不受性别、婚姻状况、教育水平、治疗类型、黏膜病变的存在以及病程的影响。

结论

LPP显著影响患者的生活质量和总体健康状况。皮肤科医生在治疗LPP患者身体症状的同时,应关注这些问题。