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植物微小RNA转录调控机制的研究进展

Advances in the Study of the Transcriptional Regulation Mechanism of Plant miRNAs.

作者信息

Teng Caixia, Zhang Chunting, Guo Fei, Song Linhong, Fang Yanni

机构信息

College of Horticulture and Forestry Science, Huazhong Agricultural University, Wuhan 430070, China.

出版信息

Life (Basel). 2023 Sep 15;13(9):1917. doi: 10.3390/life13091917.

Abstract

MicroRNAs (miRNA) are a class of endogenous, non-coding, small RNAs with about 22 nucleotides (nt), that are widespread in plants and are involved in various biological processes, such as development, flowering phase transition, hormone signal transduction, and stress response. The transcriptional regulation of miRNAs is an important process of miRNA gene regulation, and it is essential for miRNA biosynthesis and function. Like mRNAs, miRNAs are transcribed by RNA polymerase II, and these transcription processes are regulated by various transcription factors and other proteins. Consequently, the upstream genes regulating miRNA transcription, their specific expression, and the regulating mechanism were reviewed to provide more information for further research on the miRNA regulatory mechanism and help to further understand the regulatory networks of plant miRNAs.

摘要

微小RNA(miRNA)是一类内源性、非编码的小RNA,约含22个核苷酸(nt),广泛存在于植物中,并参与各种生物学过程,如发育、花期转变、激素信号转导和应激反应。miRNA的转录调控是miRNA基因调控的重要过程,对miRNA的生物合成和功能至关重要。与信使核糖核酸(mRNA)一样,miRNA由RNA聚合酶II转录,这些转录过程受各种转录因子和其他蛋白质的调控。因此,对调控miRNA转录的上游基因、它们的特异性表达及其调控机制进行了综述,以便为进一步研究miRNA调控机制提供更多信息,并有助于进一步了解植物miRNA的调控网络。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da43/10533097/f6781d39301b/life-13-01917-g001.jpg

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