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硅酸钙骨水泥中pH值及钙离子释放的评估：一项体外对比研究

Assessment of pH Value and Release of Calcium Ions in Calcium Silicate Cements: An In Vitro Comparative Study.

作者信息

Herrera-Trinidad Rubén, Molinero-Mourelle Pedro, Fonseca Manrique, Weber Adrian Roman, Vera Vicente, Mena María Luz, Vera-González Vicente

机构信息

Department of Conservative Dentistry and Orofacial Prosthodontics, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain.

Department of Reconstructive Dentistry and Gerodontology, School of Dental Medicine, University of Bern, 3007 Bern, Switzerland.

出版信息

Materials (Basel). 2023 Sep 14;16(18):6213. doi: 10.3390/ma16186213.

DOI:10.3390/ma16186213
PMID:37763492
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10532804/
Abstract

UNLABELLED

The goal of this study was to evaluate the pH and the release of calcium from four calcium-silicate-based cements.

METHODS

Four materials were tested (ProClinic MTA; Angelus MTA; ProRoot MTA; Biodentine). The palatal canal root of acrylic upper molars was filled with each cement. Afterwards, they were set in phosphate-buffered saline. Measurements were taken by atomic adsorption spectroscopy (AAS) at 3, 24, 72, 168, 336, 672, and 1008 h. The pH was measured at the same timepoints. Kruskal-Wallis tests were carried out in each period, as the Kolmogorov-Smirnov and Shapiro-Wilk tests showed no parametric results.

RESULTS

Significant differences ( < 0.05) in calcium release were found at the 3-, 24-, and 72-hour evaluations. All of the analyzed groups presented a release of calcium ions up to 168 h, and the general tendency was to increase up to 672 h, with a maximum release of 25.45 mg/g in the ProRoot group. We could only observe significant differences ( < 0.05) in pH value over 168 h between the Biodentine (7.93) and Angelus MTA (7.31) groups.

CONCLUSIONS

There were significant differences ( < 0.05) in calcium release. Nevertheless, no significant differences ( > 0.05) in the pH values were found at the studied timepoints, except for the values at 168 h.

摘要

未标注

本研究的目的是评估四种硅酸钙基水门汀的pH值和钙释放情况。

方法

测试了四种材料（ProClinic MTA；Angelus MTA；ProRoot MTA；Biodentine）。用每种水门汀填充丙烯酸上磨牙的腭根管。之后，将它们置于磷酸盐缓冲盐溶液中。在3、24、72、168、336、672和1008小时通过原子吸收光谱法（AAS）进行测量。在相同时间点测量pH值。由于Kolmogorov-Smirnov和Shapiro-Wilk检验未显示参数结果，因此在每个时间段进行Kruskal-Wallis检验。

结果

在3小时、24小时和72小时的评估中发现钙释放存在显著差异（<0.05）。所有分析组在168小时内均呈现钙离子释放，总体趋势是在672小时内增加，ProRoot组的最大释放量为25.45mg/g。我们仅观察到Biodentine组（7.93）和Angelus MTA组（7.31）在168小时以上的pH值存在显著差异（<0.05）。

结论

钙释放存在显著差异（<0.05）。然而，除了168小时的值外，在所研究的时间点pH值未发现显著差异（>0.05）。

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