Ghaly Mohamed S, Abozena Nura I, Ghouraba Rehab F, Kabbash Ibrahim A, El-Desouky Shaimaa S
Pediatric Dentistry, Oral Health and Preventive Dentistry Department, Faculty of Dentistry, Tanta University, Tanta, Egypt.
Oral Medicine, Periodontology, Oral Diagnosis, and Radiology Department, Faculty of Dentistry, Tanta University, Tanta, Egypt.
Sci Rep. 2025 Jul 21;15(1):26487. doi: 10.1038/s41598-025-11407-x.
Achieving an apical seal is critical for apexification treatment of nonvital immature teeth. While this is commonly accomplished using biocompatible mineral trioxide aggregate (MTA), its limitations, such as prolonged setting time, discoloration, and challenging handling, have driven the search for alternative materials. This study aimed to compare the clinical and radiographic success of bioceramic putty Well-Root PT apical plug compared to MTA in the treatment of nonvital immature permanent incisors. Fifty immature nonvital maxillary permanent central incisors in thirty-eight children aged 8-11 years were randomly divided into two groups (25 teeth/group). Group I received MTA apical plugs, and Group II was treated with Well-Root PT apical plugs. Both groups were recalled at 6 and 12 months for clinical and radiographic evaluations. Statistical analysis was done for the gathered data. Both groups showed improved clinical signs and symptoms during all follow-up periods with no statistically significant difference. Regarding the periapical radiolucency (PAR) area, at twelve months, the mean PAR area in the Well-Root PT group was (0.14 ± 0.08) compared to (2.3 ± 0.9) in the MTA group, with highly statistically significant differences (p < 0.001). The mean periapical bone radiodensity in the Well-Root PT group was (178.2 ± 5.4) compared to (164.8 ± 9.4) in the MTA group at twelve-month follow-up, with highly statistically significant differences(p < 0.001). Well-Root PT, with its reduced technical sensitivity, demonstrates satisfactory clinical and radiographic success as an apical plug for nonvital immature permanent incisors compared to MTA.
实现根尖封闭对于非活髓未成熟恒牙的根尖诱导成形治疗至关重要。虽然通常使用生物相容性三氧化矿物凝聚体（MTA）来实现这一点，但其局限性，如凝固时间长、变色和操作困难，促使人们寻找替代材料。本研究旨在比较生物陶瓷糊剂Well-Root PT根尖充填物与MTA在治疗非活髓未成熟恒切牙方面的临床和影像学成功率。将38名8-11岁儿童的50颗未成熟非活髓上颌恒中切牙随机分为两组（每组25颗牙）。第一组接受MTA根尖充填，第二组用Well-Root PT根尖充填物治疗。两组在6个月和12个月时进行复诊，进行临床和影像学评估。对收集到的数据进行统计分析。两组在所有随访期间临床体征和症状均有改善，无统计学显著差异。关于根尖周透射区（PAR）面积，在12个月时，Well-Root PT组的平均PAR面积为（0.14±0.08），而MTA组为（2.3±0.9），差异具有高度统计学意义（p<0.001）。在12个月随访时，Well-Root PT组的平均根尖周骨密度为（178.2±5.4），而MTA组为（164.8±9.4），差异具有高度统计学意义（p<0.001）。与MTA相比，Well-Root PT技术敏感性较低，作为非活髓未成熟恒切牙的根尖充填物，在临床和影像学上显示出令人满意的成功率。
