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暴露表面积、体积和环境pH值对三种市售硅酸三钙基牙科水门汀钙离子释放的影响

Effect of Exposed Surface Area, Volume and Environmental pH on the Calcium Ion Release of Three Commercially Available Tricalcium Silicate Based Dental Cements.

作者信息

Rajasekharan Sivaprakash, Vercruysse Chris, Martens Luc, Verbeeck Ronald

机构信息

Department of Paediatric Dentistry & Special Care, PAECOMEDIS Research Cluster, Ghent University, 9000 Ghent, Belgium.

Biomaterials Group, Department of Basic Medical Sciences, Ghent University, 9000 Ghent, Belgium.

出版信息

Materials (Basel). 2018 Jan 13;11(1):123. doi: 10.3390/ma11010123.

DOI:10.3390/ma11010123
PMID:29342837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5793621/
Abstract

Tricalcium silicate cements (TSC) are used in dental traumatology and endodontics for their bioactivity which is mostly attributed to formation of calcium hydroxide during TSC hydration and its subsequent release of calcium and hydroxide ions. The aim of this study was to determine the effect of volume (Vol), exposed surface area (ESA) and pH of surrounding medium on calcium ion release. Three commercially available hydraulic alkaline dental cements were mixed and condensed into cylindrical tubes of varying length and diameter ( = 6/group). For the effect of ESA and Vol, tubes were immersed in 10 mL of deionized water. To analyze the effect of environmental pH, the tubes were randomly immersed in 10 mL of buffer solutions with varying pH (10.4, 7.4 or 4.4). The solutions were collected and renewed at various time intervals. pH and/or calcium ion release was measured using a pH glass electrode and atomic absorption spectrophotometer respectively. The change of pH, short-term calcium ion release and rate at which calcium ion release reaches maximum were dependent on ESA ( < 0.05) while maximum calcium ion release was dependent on Vol of TSC ( < 0.05). Maximum calcium ion release was significantly higher in acidic solution followed by neutral and alkaline solution ( < 0.05).

摘要

硅酸三钙水门汀（TSC）因其生物活性而被用于牙外伤学和牙髓病学，其生物活性主要归因于TSC水合过程中氢氧化钙的形成以及随后钙离子和氢氧根离子的释放。本研究的目的是确定体积（Vol）、暴露表面积（ESA）和周围介质的pH对钙离子释放的影响。将三种市售的水硬性碱性牙科水门汀混合并压制成不同长度和直径的圆柱形管（每组 = 6个）。为了研究ESA和Vol的影响，将管子浸入10 mL去离子水中。为了分析环境pH的影响，将管子随机浸入10 mL不同pH（10.4、7.4或4.4）的缓冲溶液中。在不同时间间隔收集并更换溶液。分别使用pH玻璃电极和原子吸收分光光度计测量pH和/或钙离子释放。pH的变化、短期钙离子释放以及钙离子释放达到最大值的速率取决于ESA（P < 0.05），而最大钙离子释放量取决于TSC的Vol（P < 0.05）。在酸性溶液中最大钙离子释放量显著高于中性和碱性溶液（P < 0.05）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/a56ff6af7b4f/materials-11-00123-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/b8fc7a5d1157/materials-11-00123-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/740b9ace946b/materials-11-00123-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/38fadf61b426/materials-11-00123-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/645aafecfe11/materials-11-00123-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/a56ff6af7b4f/materials-11-00123-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/b8fc7a5d1157/materials-11-00123-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/740b9ace946b/materials-11-00123-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/38fadf61b426/materials-11-00123-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/645aafecfe11/materials-11-00123-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b21d/5793621/a56ff6af7b4f/materials-11-00123-g005.jpg

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