Abnormal cilia in a malignant ependymoma.

Abnormal cilia were frequently exposed in a malignant ependymoma of the cerebellar vermis by an electron microscope study. Among these erratic cilia, compound cilia, huge axoneme with bizarre shapes, were repeatedly observed. These giant cilia commonly had random orientation of many microtubular doublets as well as complicated cavities in their granular ciliary matrix. Additionally, abnormal cilia of normal-sized axoneme showed diversified arrangement of peripheral doublets and central singlets. The formation process of these abnormal cilia is discussed.