Hidradenitis Suppurativa Clinic, Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Hidradenitis suppurativa Clinic, Hospital Universitari Parc Taulí, Autonomous University of Barcelona, Sabadell, Barcelona, Spain.
Acta Derm Venereol. 2023 Sep 27;103:adv6569. doi: 10.2340/actadv.v103.6569.
Hidradenitis suppurativa is a chronic inflammatory disorder of the hair follicle with a high level of morbidity. Pilonidal sinus disease is a comorbid disorder and may be the reason for first contact with the healthcare system of patients with hidradenitis suppurativa. The aim of this study was to evaluate the frequency of association of pilonidal sinus disease and hidradenitis suppurativa and to explore whether pilonidal sinus disease defines a different clinical profile for patients with hidradenitis suppurativa. A cross-sectional study in which data regarding past history of pilonidal sinus disease, clinical and sociodemographic information were recorded during the first visit to the Hidradenitis Suppurativa Clinic of 2 tertiary hospitals. A total of 839 patients were included in the study. Of these, 51.7% (434/839) were male and mean age was 37.3 ± 13.6 years. Pilonidal sinus disease was present in 32.6% (269/839) of the patients and was associated with an early debut of hidradenitis suppurativa, a higher Hurley stage, inflammatory phenotype and a greater number of fistulas and perianal involvement. Elapsed time between pilonidal sinus disease and diagnosis of hidradenitis suppurativa was associated with higher disease severity. Pilonidal sinus disease is a frequent comorbidity and risk marker for hidradenitis suppurativa disease severity. Pilonidal sinus disease could be a sentinel event to identify patients who would benefit from close treatment and follow-up.
化脓性汗腺炎是一种毛囊慢性炎症性疾病，发病率较高。藏毛窦疾病是一种合并症，可能是化脓性汗腺炎患者首次接触医疗保健系统的原因。本研究旨在评估藏毛窦疾病与化脓性汗腺炎的关联频率，并探讨藏毛窦疾病是否为化脓性汗腺炎患者的不同临床特征。这是一项横断面研究，在 2 家三级医院的化脓性汗腺炎诊所首次就诊期间，记录了患者过去藏毛窦疾病史、临床和社会人口学信息。共纳入 839 例患者，其中 51.7%（434/839）为男性，平均年龄为 37.3±13.6 岁。839 例患者中有 32.6%（269/839）患有藏毛窦疾病，与化脓性汗腺炎发病早、Hurley 分期较高、炎症表型以及瘘管和肛周受累较多有关。藏毛窦疾病和化脓性汗腺炎诊断之间的时间间隔与疾病严重程度有关。藏毛窦疾病是一种常见的合并症和化脓性汗腺炎疾病严重程度的风险标志物。藏毛窦疾病可能是识别需要密切治疗和随访的患者的一个预警事件。
