Hidradenitis Suppurativa Clinic, Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada,
Dermatology Department, Hospital Universitario San Cecilio, Granada, Spain.
Dermatology. 2019;235(1):45-50. doi: 10.1159/000493465. Epub 2018 Oct 26.
BACKGROUND/AIMS: Hidradenitis suppurativa (HS) is a chronic inflammatory and destructive skin disorder. Early diagnosis and treatment are critical to stop its progression. Data concerning adolescent-onset HS are scarce. The aims of this study are to describe the prevalence of adolescent-onset HS and to explore potential risk factors and the disease features of these patients. PATIENTS AND METHODS: A cross-sectional study including 134 patients was performed. RESULTS: Adolescent-onset HS occurred in 51.5% (69/134) of patients. Adolescent-onset HS was associated with female sex, positive family history, presence of pilonidal sinus, acne conglobata, longer disease duration and a worse perception of disease severity. CONCLUSION: Adolescent-onset HS might be more frequent than previously reported. Female sex, positive family history and the presence of elements of the follicular occlusion tetrad identify individuals with a higher risk of early onset. These patients experience a longer disease duration and perceive their disease as severer.
背景/目的：化脓性汗腺炎（HS）是一种慢性炎症性和破坏性皮肤病。早期诊断和治疗对于阻止其进展至关重要。关于青少年发病 HS 的数据很少。本研究的目的是描述青少年发病 HS 的患病率，并探讨这些患者的潜在风险因素和疾病特征。
患者和方法：进行了一项包括 134 名患者的横断面研究。
结果：青少年发病 HS 发生在 51.5%（69/134）的患者中。青少年发病 HS 与女性、阳性家族史、藏毛窦、聚合性痤疮、疾病持续时间更长以及对疾病严重程度的感知更差有关。
结论：青少年发病 HS 的发病率可能高于以往报道。女性、阳性家族史和毛囊闭锁四联征的存在可识别出具有更高早发风险的个体。这些患者的疾病持续时间更长，对疾病的严重程度感知更差。
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