Singhi Anil Kumar, Mohapatra Soumya Kanti, Mukherjee Sanjeev S, Das Soumen, Maulick Tanumoy, De Arnab
Department of Pediatric and Congenital Heart Disease, Medica Super Specialty Hospital, Kolkata, West Bengal, India.
Department Cardiology, Medica Super Specialty Hospital, Kolkata, West Bengal, India.
Ann Pediatr Cardiol. 2023 Mar-Apr;16(2):127-130. doi: 10.4103/apc.apc_105_22. Epub 2023 Aug 16.
COVID-19 infection has myriad manifestations from self-limiting illness to stormy multi-organ failure. A 28-year-old woman negative for COVID reverse transcription-polymerase chain reaction underwent an uneventful elective device closure of atrial septal defect on intubation anesthesia. While a brief postprocedural endotracheal bleed was noted, significant hypoxia and respiratory distress ensued after extubation with biventricular dysfunction, pleural effusion, and radiographic evidence of acute respiratory distress syndrome. COVID antibodies were positive, and inflammatory markers were elevated. After a conservative multipronged medical management including anticoagulation, antibiotics, aspirin, beta-blocker, diuretics, and sildenafil, she improved in 1 week. The clinical course during this pandemic era gives a possibility of a post-COVID inflammatory syndrome as a potential etiology.
新型冠状病毒肺炎（COVID-19）感染有多种表现，从自限性疾病到严重的多器官功能衰竭。一名COVID逆转录聚合酶链反应检测阴性的28岁女性，在插管麻醉下顺利进行了房间隔缺损的择期器械封堵术。术后虽有短暂的气管内出血，但拔管后出现了严重的低氧血症和呼吸窘迫，并伴有双心室功能障碍、胸腔积液以及急性呼吸窘迫综合征的影像学证据。COVID抗体呈阳性，炎症标志物升高。经过包括抗凝、抗生素、阿司匹林、β受体阻滞剂、利尿剂和西地那非在内的多方面保守药物治疗，她在1周内病情好转。在这个大流行时代的临床病程提示，可能存在一种COVID后炎症综合征作为潜在病因。
