细胞死亡和自噬的脂质基础。
The lipid basis of cell death and autophagy.
机构信息
Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hunan Clinical Research Center of Pediatric Cancer, Changsha, Hunan, China.
出版信息
Autophagy. 2024 Mar;20(3):469-488. doi: 10.1080/15548627.2023.2259732. Epub 2023 Sep 28.
ACSL
acyl-CoA synthetase long chain family; DISC: death-inducing signaling complex; DAMPs: danger/damage-associated molecular patterns; Dtgn: dispersed trans-Golgi network; FAR1: fatty acyl-CoA reductase 1; GPX4: glutathione peroxidase 4; LPCAT3: lysophosphatidylcholine acyltransferase 3; LPS: lipopolysaccharide; MUFAs: monounsaturated fatty acids; MOMP: mitochondrial outer membrane permeabilization; MLKL, mixed lineage kinase domain like pseudokinase; oxPAPC: oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; OxPCs: oxidized phosphatidylcholines; PUFAs: polyunsaturated fatty acids; POR: cytochrome p450 oxidoreductase; PUFAs: polyunsaturated fatty acids; RCD: regulated cell death; RIPK1: receptor interacting serine/threonine kinase 1; SPHK1: sphingosine kinase 1; SOAT1: sterol O-acyltransferase 1; SCP2: sterol carrier protein 2; SFAs: saturated fatty acids; SLC47A1: solute carrier family 47 member 1; SCD: stearoyl-CoA desaturase; VLCFA: very long chain fatty acids.
ACSL
酰基辅酶 A 合成酶长链家族；DISC：死亡诱导信号复合物；DAMPs：危险/损伤相关分子模式；Dtgn：分散的反式高尔基体网络；FAR1：脂肪酸酰基辅酶 A 还原酶 1；GPX4：谷胱甘肽过氧化物酶 4；LPCAT3：溶血磷脂酰胆碱酰基转移酶 3；LPS：脂多糖；MUFAs：单不饱和脂肪酸；MOMP：线粒体外膜通透性；MLKL，混合谱系激酶结构域样假激酶；oxPAPC：氧化 1-棕榈酰-2-花生四烯酰-sn-甘油-3-磷酸胆碱；OxPCs：氧化磷脂；PUFAs：多不饱和脂肪酸；POR：细胞色素 p450 氧化还原酶；PUFAs：多不饱和脂肪酸；RCD：调控细胞死亡；RIPK1：受体相互作用丝氨酸/苏氨酸激酶 1；SPHK1：鞘氨醇激酶 1；SOAT1：固醇 O-酰基转移酶 1；SCP2：固醇载体蛋白 2；SFAs：饱和脂肪酸；SLC47A1：溶质载体家族 47 成员 1；SCD：硬脂酰辅酶 A 去饱和酶；VLCFA：非常长链脂肪酸。
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