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利用初级和二级保健的常规数据评估英格兰获得公共资助的体重管理服务的情况(2007-2020 年):一项观察性队列研究。

Access to publicly funded weight management services in England using routine data from primary and secondary care (2007-2020): An observational cohort study.

机构信息

Health Economics Bristol, Population Health Sciences, University of Bristol, Bristol, United Kingdom.

National Institute for Health Research Bristol Biomedical Research Centre, Population Health Sciences, University of Bristol, Bristol, United Kingdom.

出版信息

PLoS Med. 2023 Sep 28;20(9):e1004282. doi: 10.1371/journal.pmed.1004282. eCollection 2023 Sep.

Abstract

BACKGROUND

Adults living with overweight/obesity are eligible for publicly funded weight management (WM) programmes according to national guidance. People with the most severe and complex obesity are eligible for bariatric surgery. Primary care plays a key role in identifying overweight/obesity and referring to WM interventions. This study aimed to (1) describe the primary care population in England who (a) are referred for WM interventions and (b) undergo bariatric surgery and (2) determine the patient and GP practice characteristics associated with both.

METHODS AND FINDINGS

An observational cohort study was undertaken using routinely collected primary care data in England from the Clinical Practice Research Datalink linked with Hospital Episode Statistics. During the study period (January 2007 to June 2020), 1,811,587 adults met the inclusion criteria of a recording of overweight/obesity in primary care, of which 54.62% were female and 20.10% aged 45 to 54. Only 56,783 (3.13%) were referred to WM, and 3,701 (1.09% of those with severe and complex obesity) underwent bariatric surgery. Multivariable Poisson regression examined the associations of demographic, clinical, and regional characteristics on the likelihood of WM referral and bariatric surgery. Higher body mass index (BMI) and practice region had the strongest associations with both outcomes. People with BMI ≥40 kg/m2 were more than 6 times as likely to be referred for WM (10.05% of individuals) than BMI 25.0 to 29.9 kg/m2 (1.34%) (rate ratio (RR) 6.19, 95% confidence interval (CI) [5.99,6.40], p < 0.001). They were more than 5 times as likely to undergo bariatric surgery (3.98%) than BMI 35.0 to 40.0 kg/m2 with a comorbidity (0.53%) (RR 5.52, 95% CI [5.07,6.02], p < 0.001). Patients from practices in the West Midlands were the most likely to have a WM referral (5.40%) (RR 2.17, 95% CI [2.10,2.24], p < 0.001, compared with the North West, 2.89%), and practices from the East of England least likely (1.04%) (RR 0.43, 95% CI [0.41,0.46], p < 0.001, compared with North West). Patients from practices in London were the most likely to undergo bariatric surgery (2.15%), and practices in the North West the least likely (0.68%) (RR 3.29, 95% CI [2.88,3.76], p < 0.001, London compared with North West). Longer duration since diagnosis with severe and complex obesity (e.g., 1.67% of individuals diagnosed in 2007 versus 0.34% in 2015, RR 0.20, 95% CI [0.12,0.32], p < 0.001), and increasing comorbidities (e.g., 2.26% of individuals with 6+ comorbidities versus 1.39% with none (RR 8.79, 95% CI [7.16,10.79], p < 0.001) were also strongly associated with bariatric surgery. The main limitation is the reliance on overweight/obesity being recorded within primary care records to identify the study population.

CONCLUSIONS

Between 2007 and 2020, a very small percentage of the primary care population eligible for WM referral or bariatric surgery according to national guidance received either. Higher BMI and GP practice region had the strongest associations with both. Regional inequalities may reflect differences in commissioning and provision of WM services across the country. Multi-stakeholder qualitative research is ongoing to understand the barriers to accessing WM services and potential solutions. Together with population-wide prevention strategies, improved access to WM interventions is needed to reduce obesity levels.

摘要

背景

根据国家指导方针,超重/肥胖的成年人有资格参加公共资助的体重管理(WM)计划。最严重和最复杂肥胖的人有资格接受减重手术。初级保健在识别超重/肥胖并转介 WM 干预方面发挥着关键作用。本研究旨在:(1)描述在英格兰有资格接受 WM 干预和减重手术的初级保健人群;(2)确定与这两者相关的患者和 GP 实践特征。

方法和发现

本研究采用观察性队列研究,使用英格兰常规收集的初级保健数据,该数据来自临床实践研究数据库,并与医院事件统计数据相关联。在研究期间(2007 年 1 月至 2020 年 6 月),有 1811587 名成年人符合在初级保健中记录超重/肥胖的纳入标准,其中 54.62%为女性,20.10%年龄在 45 至 54 岁之间。只有 56783 人(占严重和复杂肥胖人群的 3.13%)被转介接受 WM,3701 人(占严重和复杂肥胖人群的 1.09%)接受了减重手术。多变量泊松回归分析了人口统计学、临床和地区特征与 WM 转介和减重手术的可能性之间的关联。更高的体重指数(BMI)和实践地区与这两个结果的关联最强。BMI≥40kg/m2的人比 BMI 为 25.0 至 29.9kg/m2(1.34%)的人更有可能被转介接受 WM(10.05%)(RR 6.19,95%置信区间 [5.99,6.40],p<0.001)。他们比 BMI 为 35.0 至 40.0kg/m2且伴有合并症的人(0.53%)更有可能接受减重手术(3.98%)(RR 5.52,95%置信区间 [5.07,6.02],p<0.001)。来自西米德兰兹郡的患者最有可能接受 WM 转介(5.40%)(RR 2.17,95%置信区间 [2.10,2.24],p<0.001,与西北区相比,2.89%),而来自东英格兰区的患者最不可能(1.04%)(RR 0.43,95%置信区间 [0.41,0.46],p<0.001,与西北区相比)。来自伦敦的患者最有可能接受减重手术(2.15%),而来自西北区的患者最不可能(0.68%)(RR 3.29,95%置信区间 [2.88,3.76],p<0.001,与西北区相比)。严重和复杂肥胖的诊断时间越长(例如,2007 年诊断的个体中为 1.67%,而 2015 年为 0.34%,RR 0.20,95%置信区间 [0.12,0.32],p<0.001),合并症数量增加(例如,6 种以上合并症的个体中为 2.26%,而无合并症的个体中为 1.39%(RR 8.79,95%置信区间 [7.16,10.79],p<0.001))也与减重手术强烈相关。主要限制是依赖于在初级保健记录中记录超重/肥胖来确定研究人群。

结论

2007 年至 2020 年期间,根据国家指导方针,有资格接受 WM 转介或减重手术的初级保健人群中,只有极少数人接受了这两种治疗。更高的 BMI 和 GP 实践地区与这两者的关联最强。地区差异可能反映了全国范围内 WM 服务的委托和提供的差异。正在进行多利益攸关方定性研究,以了解获得 WM 服务的障碍和潜在解决方案。结合全人群预防策略,需要改善 WM 干预措施的可及性,以降低肥胖水平。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7b8/10538857/46805ec747be/pmed.1004282.g001.jpg

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