Coverlizza S, Ferrari A, Scevola F, Gemme C, Cavallero M, Spandre M, Risio M, Rossini F P
Am J Gastroenterol. 1986 Nov;81(11):1098-103.
Collagenous colitis is a newly identified condition, with clinical features of chronic watery diarrhea and abdominal pain. Histologically the main characteristic is the presence of a thick collagen band below the surface epithelium. Collagenous colitis occurs in adults, especially women. Endoscopy reveals no particular changes in the intestinal mucosa. Symptoms may persist for years with periods of remission and recurring acute attacks. The cause of this condition is still unknown, and because of no real knowledge only symptoms can be treated, usually with little success.
胶原性结肠炎是一种新发现的疾病,具有慢性水样腹泻和腹痛的临床特征。组织学上的主要特征是表面上皮下方存在一条增厚的胶原带。胶原性结肠炎发生于成年人,尤其是女性。内镜检查显示肠道黏膜无特殊变化。症状可能会持续数年,有缓解期和反复发作的急性发作期。这种疾病的病因仍然不明,由于缺乏实际了解,只能对症治疗,通常效果不佳。