Heisel J S, Locke S E, Kraus L J, Williams R M
Am J Psychiatry. 1986 Nov;143(11):1382-6. doi: 10.1176/ajp.143.11.1382.
Natural killer (NK) cells are important in immune function and appear, in part, to be regulated by the CNS. The authors compared NK cell activity and MMPI scores of 111 healthy college students and found weak but statistically significant correlations between NK values and psychopathology for 10 of 12 scales. Students with the highest NK values had a "healthier" MMPI profile than those with the lowest. Students with high MMPI scores (T greater than 70) had NK values below the sample median. These findings support theories of interaction between mental state and immune status, but the mechanisms and direction of interaction remain largely unexplored.
自然杀伤（NK）细胞在免疫功能中起着重要作用，并且部分似乎受中枢神经系统调节。作者比较了111名健康大学生的NK细胞活性和明尼苏达多相人格调查表（MMPI）得分，发现12个量表中有10个量表的NK值与精神病理学之间存在微弱但具有统计学意义的相关性。NK值最高的学生比NK值最低的学生具有更“健康”的MMPI剖面图。MMPI得分高（T大于70）的学生NK值低于样本中位数。这些发现支持了心理状态与免疫状态之间相互作用的理论，但相互作用的机制和方向在很大程度上仍未得到探索。
