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脑深部电刺激的人类学;2023年丘脑底核电刺激30周年。

Anthropology of Deep Brain Stimulation; the 30th Anniversary of STN DBS in 2023.

作者信息

Hariz Marwan, Blomstedt Yulia, Blomstedt Patric, Hariz Gun-Marie

机构信息

Department of Clinical Neuroscience Umeå University Umeå Sweden.

UCL Institute of Neurology, Queen Square London United Kingdom.

出版信息

Mov Disord Clin Pract. 2023 Sep 1;10(9):1285-1292. doi: 10.1002/mdc3.13858. eCollection 2023 Sep.

Abstract

BACKGROUND

The year 2023 marks the 30th anniversary of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinsons disease (PD). This procedure prompted a universal interest in DBS for various brain disorders and resulted in a unique expansion of clinical and scientific collaboration between many disciplines, with impact on many aspects of society.

OBJECTIVE

To study the anthropology of DBS, that is, its ethno-geographic origins, its evolution, its impact on clinicians and scientists, and its influence on society at large.

MATERIAL AND METHODS

The authors scrutinized the geo-ethnic origins of the pioneers of modern DBS, and they evaluated, based on the literature and on a long-term praxis, the development of DBS and its impact on clinicians, on healthcare, and on society.

RESULTS

Scientists and clinicians from various geo-ethnic origins pioneered modern DBS, leading to worldwide spread of this procedure and to the establishment of large multidisciplinary teams in many centers. Neurologists became actively involved in surgery and took on new laborious tasks of programming ever more complicated DBS systems. Publications sky-rocketed and the global spread of DBS impacted positively on several aspects of society, including healthcare, awareness of neurological diseases, interdisciplinary relations, conferences, patient organizations, unemployment, industry, etc.

CONCLUSIONS

STN DBS has boosted the field of deep brain electrotherapy for many neurological and psychiatric illnesses, and DBS has generated a global benefit on many aspects of society, well beyond its clinical benefits on symptoms of diseases. With the ever-increasing indications for DBS, more positive global impact is expected.

摘要

背景

2023年是丘脑底核(STN)深部脑刺激(DBS)治疗帕金森病(PD)30周年。这一手术引发了人们对DBS治疗各种脑部疾病的广泛关注,并促成了多学科之间独特的临床与科学合作的扩展,对社会的诸多方面产生了影响。

目的

研究DBS的人类学,即其种族地理起源、演变、对临床医生和科学家的影响以及对整个社会的影响。

材料与方法

作者仔细研究了现代DBS先驱者的种族地理起源,并基于文献和长期实践,评估了DBS的发展及其对临床医生、医疗保健和社会的影响。

结果

来自不同种族地理背景的科学家和临床医生开创了现代DBS,使得该手术在全球范围内得以推广,并在许多中心建立了大型多学科团队。神经科医生积极参与手术,并承担起为日益复杂的DBS系统进行编程这一全新的艰巨任务。相关出版物数量激增,DBS在全球的传播对社会的多个方面产生了积极影响,包括医疗保健、对神经系统疾病的认识、跨学科关系、会议、患者组织、失业、产业等。

结论

丘脑底核DBS推动了针对多种神经和精神疾病的深部脑电治疗领域的发展,并且DBS在社会的诸多方面都产生了全球性益处,远远超出了其对疾病症状的临床疗效。随着DBS适应证的不断增加,预计将产生更多积极的全球影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76c8/10525058/3d7ee104d8b7/MDC3-10-1285-g002.jpg

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