Department of Gastroenterology, The First People's Hospital of Huzhou, First Affiliated Hospital of Huzhou University, Huzhou, P.R. China.
Department of Gastroenterology, People's Hospital of Wuxing District, Wuxing Branch of the First People's Hospital of Huzhou, Huzhou, P.R. China.
Medicine (Baltimore). 2023 Sep 29;102(39):e35336. doi: 10.1097/MD.0000000000035336.
Screening, followed by colonoscopic polypectomy, has been widely performed in China. However, factors influencing age at onset of colorectal polyps and benefit-finding after polypectomy have been insufficiently studied or ignored. A total of 152 patients with colorectal polyps first detected in First Affiliated Hospital of Huzhou University from July to September 2022 were enrolled in this study. We selected 11 factors associated with the risk of colorectal polyps, including gender, body mass index, occupational stress, education level, income satisfaction, smoking, alcohol consumption, exercise frequency, diet, family history and polyp characteristics. Benefit-finding after polypectomy was obtained by follow-up for 142 of these patients. Multivariate linear regression analysis showed that being overweight (i.e., body mass index ≥25 kg/m2), higher education level, lower exercise frequency, and refrigerated food preference were associated with early-onset colorectal polyps. Patients with a preference for pickled food and age ≥50 years at first colorectal polyp detection had lower benefit findings after colonoscopic polypectomy. Colorectal polyps may develop earlier in people who are overweight, well-educated, exercise less, and prefer refrigerated food. In addition, patients who prefer pickled food and age at onset ≥50 years have lower benefit-finding requiring more attention in future colonoscopy follow-ups.
在中国，广泛开展了筛查，随后进行结肠镜息肉切除术。然而，影响结直肠息肉发病年龄和息肉切除后获益的因素研究不足或被忽视。本研究纳入了 2022 年 7 月至 9 月在湖州第一医院首次发现结直肠息肉的 152 例患者。我们选择了 11 个与结直肠息肉风险相关的因素，包括性别、体重指数、职业压力、教育水平、收入满意度、吸烟、饮酒、运动频率、饮食、家族史和息肉特征。对其中 142 例患者进行了随访，以获得息肉切除后的获益情况。多变量线性回归分析显示，超重（即体重指数≥25kg/m2）、较高的教育水平、较低的运动频率和喜欢冷藏食品与结直肠息肉的早发有关。喜欢腌制食品和首次结直肠息肉检测年龄≥50 岁的患者，结肠镜息肉切除后的获益较低。超重、受教育程度较高、运动较少和喜欢冷藏食品的人可能更早出现结直肠息肉。此外，喜欢腌制食品且发病年龄≥50 岁的患者在未来结肠镜随访中需要更多关注，以获得较低的获益。
