3B's Research Group, I3Bs-Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, Barco, Portugal.
ICVS/3B's - PT Government Associate Laboratory, Braga, Portugal.
Tissue Eng Part B Rev. 2024 Jun;30(3):299-314. doi: 10.1089/ten.TEB.2023.0077. Epub 2023 Dec 7.
Impact statement This review discusses the research done using marine collagens (MCs) on biomaterials for bone, cartilage, and osteochondral tissue regenerative applications with the underlying technologies that enable their development, and explains the methodologies used to characterize MCs highlighting their importance, namely regarding the performance of derived biomaterials, and the inherent properties of such collagens. In the second part, the applicability of MCs as biomaterials for hard tissue applications was studied, focusing on the mostly applied fabrication techniques. In conclusion, this review describes the major challenges to be overcome and the forecast for the upcoming years concerning the use of MCs.
影响声明 本综述讨论了使用海洋胶原蛋白 (MCs) 进行骨、软骨和骨软骨组织再生应用的研究,讨论了支持其开发的基础技术,并解释了用于表征 MCs 的方法学,强调了它们的重要性,即关于衍生生物材料的性能以及这些胶原蛋白的固有特性。在第二部分中,研究了 MCs 作为硬组织应用生物材料的适用性,重点研究了最常应用的制造技术。总之,本综述描述了使用 MCs 所面临的主要挑战和未来几年的展望。