Department of Veterinary Medicine, Çaycuma Food and Agriculture Vocational School, Zonguldak Bülent Ecevit University, Zonguldak, Turkey.
Department of Basic Sciences, Faculty of Engineering, Necmettin Erbakan University, Konya, Turkey.
Bull Environ Contam Toxicol. 2023 Sep 30;111(4):52. doi: 10.1007/s00128-023-03807-4.
Metal composites have been extensively used in various fields such as automotive industry, medicine and pharmacy. However, the high exposure of these chemicals may have an adverse effect on the living organisms. In this study, the effect of titanium aluminum carbide (TiAlC) on the model organism Galleria mellonella was investigated. The change in the metabolic enzymes such as alanine transferase, aspartate transferase, gamma-glutamyl transferase, lactate dehydrogenase, amylase, creatine kinase, alkaline phosphatase in the hemolymph of G. mellonella which was exposed to TiAlC was determined. The contents of the bilirubin, albumin, uric acid and the total protein were also measured after the TiAlC exposure on the model organism. The results of our study clearly indicate that TiAlC has adverse effects on the model organism G. mellonella.
金属复合材料在汽车工业、医学和制药等各个领域得到了广泛应用。然而，这些化学物质的高暴露可能对生物体产生不良影响。在这项研究中，研究了钛碳化铝（TiAlC）对模式生物黄粉虫的影响。测定了暴露于 TiAlC 的黄粉虫血淋巴中丙氨酸转氨酶、天冬氨酸转氨酶、γ-谷氨酰转移酶、乳酸脱氢酶、淀粉酶、肌酸激酶、碱性磷酸酶等代谢酶的变化。在模式生物上暴露于 TiAlC 后，还测量了胆红素、白蛋白、尿酸和总蛋白的含量。我们的研究结果清楚地表明，TiAlC 对模式生物黄粉虫有不良影响。
