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慢性阻塞性肺疾病患者继续吸烟、戒烟以及改用加热烟草制品的特征及原因。

Characteristics of and reasons for patients with chronic obstructive pulmonary disease to continue smoking, quit smoking, and switch to heated tobacco products.

作者信息

Hirai Kuniaki, Tanaka Akihiko, Homma Tetsuya, Kawahara Tomoko, Oda Naruhito, Mikuni Hatsuko, Uchida Yoshitaka, Saito Haruhisa, Fukuda Yosuke, Fujiwara Akiko, Sato Yoko, Uno Tomoki, Inoue Hideki, Ohta Shin, Yamaguchi Fumihiro, Suzuki Shintaro, Ohnishi Tsukasa, Sagara Hironori

机构信息

Division of Respiratory Medicine and Allergology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.

Division of Respiratory Medicine, Department of Medicine, Yamanashi Red Cross Hospital, Yamanashi, Japan.

出版信息

Tob Induc Dis. 2021 Nov 1;19:85. doi: 10.18332/tid/142848. eCollection 2021.

Abstract

INTRODUCTION

Smoking is the leading cause of chronic obstructive pulmonary disease (COPD), and smoking cessation is the most effective treatment for patients with COPD. However, few studies have investigated the continuation/cessation of smoking and heated tobacco products (HTP) in patients with COPD. The objective of this study was to examine the characteristics of patients with COPD, those who are current smokers and those who switched from cigarettes to HTP, and to examine the reason for the continuation or cessation of smoking.

METHODS

This multicenter, cross-sectional study included 411 outpatients with COPD. Data for this study were part of a study conducted for a comprehensive evaluation of the smoking status and clinical factors in patients with COPD and their families.

RESULTS

Logistic regression analysis revealed that a younger age, longer duration of smoking, fewer daily cigarettes, and lower modified Medical Research Council (mMRC) dyspnea score, and a lower Simplified Nutritional Appetite Questionnaire (SNAQ) score for appetite, were characteristics of current smokers (age OR=0.94; duration of smoking OR=1.07; number of cigarettes per day OR=0.94; mMRC OR=0.68; SNAQ OR=0.83; p<0.05). The logistic regression analysis model showed that a younger age and higher education level were associated with the use of HTP (age OR=0.83; higher education level OR=4.63; p<0.05). Many of the current smokers displayed smoking behaviors that are not guaranteed to be safe, such as reducing smoking or switching to lighter cigarettes or HTP.

CONCLUSIONS

Patients with COPD who continue smoking tended to have low appetite as well as smoking behaviors that are not guaranteed to be safe. Physicians should provide appropriate guidance to these patients on smoking cessation.

摘要

引言

吸烟是慢性阻塞性肺疾病(COPD)的主要病因,戒烟是COPD患者最有效的治疗方法。然而,很少有研究调查COPD患者继续吸烟/戒烟以及使用加热烟草制品(HTP)的情况。本研究的目的是检查COPD患者、当前吸烟者以及从香烟改用HTP者的特征,并探究继续吸烟或戒烟的原因。

方法

这项多中心横断面研究纳入了411例COPD门诊患者。本研究的数据是一项对COPD患者及其家属吸烟状况和临床因素进行综合评估的研究的一部分。

结果

逻辑回归分析显示,年龄较小、吸烟时间较长、每日吸烟量较少、改良医学研究委员会(mMRC)呼吸困难评分较低以及简化营养食欲问卷(SNAQ)食欲评分较低是当前吸烟者的特征(年龄OR = 0.94;吸烟时间OR = 1.07;每日吸烟量OR = 0.94;mMRC OR = 0.68;SNAQ OR = 0.83;p < 0.05)。逻辑回归分析模型表明,年龄较小和教育水平较高与使用HTP有关(年龄OR = 0.83;教育水平较高OR = 4.63;p < 0.05)。许多当前吸烟者表现出不一定安全的吸烟行为,如减少吸烟量或改用淡烟或HTP。

结论

继续吸烟的COPD患者往往食欲较低,且有不一定安全的吸烟行为。医生应就戒烟向这些患者提供适当指导。

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