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加热烟草制品行为研究的范围综述

A Scoping Review of Behavioural Studies on Heated Tobacco Products.

作者信息

Fearon Ian M, Cordery Sarah F, Fitzpatrick Martin, Weaver Sarah, Stevenson Matthew, Grandolfo Erika, Malt Layla, Thompson Keith, Nahde Thomas

机构信息

Scientific Research, whatIF? Consulting Ltd., Harwell, GBR.

Group Science and Regulatory Affairs, Imperial Brands PLC, Bristol, GBR.

出版信息

Cureus. 2024 Jul 30;16(7):e65773. doi: 10.7759/cureus.65773. eCollection 2024 Jul.

Abstract

Heated tobacco products (HTPs) are electronic devices that heat tobacco sticks to temperatures much lower than those which cause pyrolysis and combustion in cigarettes. While this electrical heating causes the formation of an inhalable aerosol which contains nicotine, the aerosol from HTPs contains significantly fewer and lower levels of the harmful and potentially harmful chemicals found in cigarette smoke. As a result, HTP use potentially conveys reduced risks to health compared to cigarette smoking. While this relative reduction in individual health risk is becoming clearer, what is less certain is the impact of HTPs on overall population‑level health, taking into account both the potential positive impact on adult smokers who completely switch to using HTPs and any unintended impacts such as use by tobacco non‑users and particularly by youth. The aim of this scoping review was to collate and evaluate the published scientific evidence to date, with a cut‑off of 1 January 2024, investigating the impact of HTPs on population‑level health. This evaluation suggests that HTP use is almost exclusively observed among those with a history of cigarette smoking, and there is a growing body of evidence for the ability of HTPs to provide support for adult smokers to transition away from cigarette smoking, in the absence of any significant "gateway" into tobacco use initiation. Many studies have reported a significant degree of dual use of cigarettes and HTPs, and efforts to assess the reasons for such patterns of use, whether these provide overall exposure reductions, and whether dual use acts as a bridge towards a complete transition away from cigarette smoking, requires further investigation. In addition, correction of the widespread and increasing misperceptions of HTPs among adult smokers is recommended to promote HTP uptake as a potentially less harmful alternative to smoking in this population.

摘要

加热烟草制品(HTPs)是一种电子设备,它将烟草棒加热到远低于香烟中导致热解和燃烧的温度。虽然这种电加热会形成一种可吸入的气溶胶,其中含有尼古丁,但加热烟草制品产生的气溶胶所含的有害和潜在有害化学物质的数量和水平要比香烟烟雾中的少得多。因此,与吸烟相比,使用加热烟草制品可能对健康造成的风险更低。虽然个体健康风险的这种相对降低越来越明显,但考虑到对完全改用加热烟草制品的成年吸烟者的潜在积极影响以及任何意外影响,如非烟草使用者尤其是青少年的使用情况,加热烟草制品对总体人群健康的影响尚不确定。本范围综述的目的是整理和评估截至2024年1月1日已发表的科学证据,以调查加热烟草制品对人群健康的影响。该评估表明,加热烟草制品的使用几乎只在有吸烟史的人群中观察到,并且越来越多的证据表明,在没有任何重大“入门”导致开始使用烟草的情况下,加热烟草制品有能力支持成年吸烟者戒烟。许多研究报告了大量同时使用香烟和加热烟草制品的情况,评估这种使用模式的原因、这些模式是否能总体减少接触以及同时使用是否是完全戒烟的桥梁等问题,需要进一步研究。此外,建议纠正成年吸烟者中对加热烟草制品广泛且日益增加的误解,以促进该人群将加热烟草制品作为潜在危害较小的吸烟替代品来使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a1b/11361622/9f36c96d0f45/cureus-0016-00000065773-i01.jpg

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