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[手术切除胃中的恶性类癌瘤与腺瘤合并:一例免疫组织学研究]

[Combined malignant carcinoid and adenomas in the operated stomach: the immunohistological study of a case].

作者信息

Frank G A, Pugachev K K, Shimbireva I B, Avdeev G I

出版信息

Arkh Patol. 1986;48(8):73-5.

PMID:3778239
Abstract

The distribution of carcinoembryonic antigen (CEA), organ specific colonic antigen (C) and two pepsinogens (P) was studied in the peritumorous mucosa and in the tumours (one carcinoid and 3 adenomas) in the stomach of a patient, that had undergone the Bilroth-II resection 10 years before. No antigens were found in the carcinoid. C-antigen was found in the adenomas. The peritumorous gastric mucosa, morphologically not changed contained P, but not C and CEA. Mucosal areas adjacent to the adenomas had dysplastic or metaplastic changes, contained CEA and C, but didn't contain P.

摘要

对一名10年前接受过毕罗Ⅱ式切除术患者胃内的肿瘤旁黏膜及肿瘤(1例类癌和3例腺瘤)中癌胚抗原(CEA)、器官特异性结肠抗原(C)和两种胃蛋白酶原(P)的分布进行了研究。在类癌中未发现抗原。在腺瘤中发现了C抗原。形态学上未改变的肿瘤旁胃黏膜含有P,但不含C和CEA。腺瘤相邻的黏膜区域有发育异常或化生改变,含有CEA和C,但不含P。

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