Porter R J, Stirrat G M
Br J Obstet Gynaecol. 1986 Nov;93(11):1124-31. doi: 10.1111/j.1471-0528.1986.tb08632.x.
Retrospective analysis of 82 pregnancies in women with either ulcerative colitis or Crohn's disease suggested that, in general, neither disease had a major effect on pregnancy outcome. The birth-weights of babies born to women with inflammatory bowel disease were marginally lower than those born to women in a control group matched for age and parity, but the difference was statistically significant only in women with Crohn's disease. In both disease groups there was a higher frequency of low haemoglobin levels in pregnancy than in the matched control groups. There were no statistically significant effects of ulcerative colitis or Crohn's disease on duration of pregnancy, mode of delivery or raised blood pressure and/or proteinuria. In the absence of a relapse, a diagnosis of inflammatory bowel disease should not influence obstetric management.
对82例患有溃疡性结肠炎或克罗恩病的孕妇进行的回顾性分析表明，总体而言，这两种疾病对妊娠结局均无重大影响。炎症性肠病女性所生婴儿的出生体重略低于年龄和胎次匹配的对照组女性所生婴儿，但这种差异仅在克罗恩病女性中具有统计学意义。在这两个疾病组中，孕期血红蛋白水平低的发生率均高于匹配的对照组。溃疡性结肠炎或克罗恩病对孕期、分娩方式或血压升高和/或蛋白尿无统计学意义上的显著影响。在无疾病复发的情况下，炎症性肠病的诊断不应影响产科管理。
