Bedenne L, Faivre J, Boutron M C, Hillon P, Milan C, Riou F, Klepping C
Bull Cancer. 1986;73(5):526-34.
The registry of digestive tract tumors established for the department of Côte-d' Or was used to study the incidence and characteristics of oesophageal cancer in the area. The crude annual incidence rate was 15.5/100,000 for males, ans 1.1/100,000 for females. The corresponding age standardized rate (world standard) were 12.7 and 0.6. The sex ratio was 21.2. As compared to other cancer registries the Côte-d' Or is in intermediate range for males, in the low range for females. The incidence of oesophageal cancer was similar in urban and rural areas. The risk of oesophageal cancer in males was five times higher in workers than in high executives and professionals. There was no significant variation in oesophageal cancer incidence over the 8 years of the study. Rates tended to decrease slightly in both sexes. Most cancers were squamous cell carcinomas (92%). Adenocarcinomas represented 5% of the cases. The risk of an associated tumour of the upper respiratory and digestive tract was important (17.5%). Only 10.4% of the patients underwent curative surgery, while 53.4% were referred for radiotherapy alone. The overall 1-year survival rate was 18.4%, and the 5-year survival rate was 2.8%. The 5-year survival rate was 7.2% after curative surgery, and 3.2% after radiotherapy. These results underline the fact that the prognosis of oesophageal cancer in a well defined population where only one patient out of ten can benefit from curative surgery, remains poor.
为科多尔省设立的消化道肿瘤登记处用于研究该地区食管癌的发病率和特征。男性的年粗发病率为15.5/10万，女性为1.1/10万。相应的年龄标准化率（世界标准）分别为12.7和0.6。性别比为21.2。与其他癌症登记处相比，科多尔省男性发病率处于中等范围，女性处于低范围。食管癌的发病率在城市和农村地区相似。男性工人患食管癌的风险比高级管理人员和专业人员高五倍。在研究的8年中，食管癌发病率没有显著变化。两性发病率均有轻微下降趋势。大多数癌症为鳞状细胞癌（92%）。腺癌占病例的5%。上呼吸道和消化道相关肿瘤的风险较高（17.5%）。只有10.4%的患者接受了根治性手术，而53.4%的患者仅接受了放射治疗。总体1年生存率为18.4%，5年生存率为2.8%。根治性手术后5年生存率为7.2%，放射治疗后为3.2%。这些结果突显了这样一个事实，即在一个明确界定的人群中，食管癌的预后仍然很差，每十名患者中只有一名能够从根治性手术中获益。
