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术前超声特征与甲状腺乳头状癌术后复发的相关性研究:一项回顾性研究。

Correlation research between preoperative ultrasonographic features and postoperative recurrence of papillary thyroid carcinoma: a retrospective study.

机构信息

Department of Ultrasound, The Third Hospital of Jilin University, 126 Xian Tai Street, Changchun, 130031, China.

Department of Ultrasound, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

出版信息

J Ultrasound. 2023 Dec;26(4):891-896. doi: 10.1007/s40477-023-00831-2. Epub 2023 Oct 4.

Abstract

OBJECTIVE

This study sought to evaluate the risk factors for recurrent papillary thyroid carcinoma by preoperative ultrasonography.

METHODS

A retrospective study enrolled a total of 146 patients with thyroid papillary carcinoma confirmed by postoperative pathology, and divided into a recurrence group (n = 35) and a non-recurrence group (n = 111) to study their preoperative ultrasound report examination, including the presence of thyroiditis, tumor location, the maximum diameter of the primary tumor, tumor number, the presence of focal strong echogenicity within the lesion, the presence of abnormal lymph nodes, the presence of ultrasound imaging manifestations of thyroid invasion, and to explore the risk factors associated with recurrent papillary thyroid cancer. Moreover, the consistency of ultrasound examination and postoperative pathological findings was explored.

RESULTS

There were significant differences in the maximum diameter of the primary tumor and thyroid invasion between the recurrent and non-recurrent papillary thyroid carcinoma groups (P < 0.05), and the preoperative tumor diameter diagnostic cutoff value is 13.750 mm. At the same time, ultrasound and pathology have good consistency in the number of papillary thyroid carcinoma tumors, moderate consistency in lymph node metastasis, and excellent consistency in the presence or absence of thyroid invasion.

CONCLUSIONS

The maximum diameter of the primary tumor and thyroid invasion can be used as indicators to evaluate the risk of recurrence of thyroid papillary carcinoma by ultrasonic examination. In addition, the number of tumors and the presence of thyroid invasion in ultrasonic and pathological diagnosis showed good consistency.

摘要

目的

本研究旨在通过术前超声评估复发性甲状腺乳头状癌的危险因素。

方法

回顾性研究共纳入 146 例术后病理证实为甲状腺乳头状癌的患者,分为复发组(n=35)和非复发组(n=111),研究其术前超声报告检查,包括是否存在甲状腺炎、肿瘤位置、原发肿瘤最大直径、肿瘤数量、病灶内是否存在局灶性强回声、是否存在异常淋巴结、是否存在甲状腺侵犯的超声影像学表现,并探讨与复发性甲状腺乳头状癌相关的危险因素。同时,还探讨了超声检查与术后病理结果的一致性。

结果

复发组与非复发组的原发肿瘤最大直径和甲状腺侵犯差异有统计学意义(P<0.05),术前肿瘤直径诊断截断值为 13.750 mm。同时,超声和病理在甲状腺乳头状癌肿瘤数量上具有良好的一致性,在淋巴结转移上具有中度一致性,在甲状腺侵犯的存在或不存在上具有极好的一致性。

结论

超声检查中原发肿瘤最大直径和甲状腺侵犯可作为评估甲状腺乳头状癌复发风险的指标。此外,超声和病理诊断在肿瘤数量和甲状腺侵犯方面具有良好的一致性。

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Molecular Predictors for Advanced Papillary Thyroid Carcinoma Recurrence.晚期甲状腺乳头状癌复发的分子预测指标
Front Endocrinol (Lausanne). 2019 Dec 5;10:839. doi: 10.3389/fendo.2019.00839. eCollection 2019.

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