Swash M, Leader M, Brown A, Swettenham K W
Brain. 1986 Oct;109 ( Pt 5):939-52. doi: 10.1093/brain/109.5.939.
In a three-dimensional study of the distribution of anterior horn cells in the C8 segment of the human spinal cord we have recognized lateral and medial zones of motor neuron groupings, but have not been able to recognize subgroups of neurons within these groupings resembling the anatomical columns described by earlier investigators. This observation does not invalidate the concept of functional groupings within these anterior horn cell pools. In studies of the same segment in cords obtained at autopsy from patients with motor neuron disease, zones of focal loss of motor neurons were identified, without consistent severity or distribution at different sectional levels. These findings imply varying resistance to the disease in different pools of motor neurons.
在一项关于人类脊髓C8节段前角细胞分布的三维研究中，我们识别出了运动神经元群的外侧和内侧区域，但未能在这些群内识别出类似于早期研究者所描述的解剖学柱的神经元亚群。这一观察结果并未使这些前角细胞池内功能分组的概念无效。在对运动神经元疾病患者尸检获得的脊髓同一节段的研究中，识别出了运动神经元局灶性缺失区域，在不同切片水平上其严重程度和分布并不一致。这些发现意味着不同运动神经元池对该疾病的抵抗力不同。
