University of Hawaii Cancer Center, Honolulu, Hawaii, USA.
Department of Radiology and Bioimaging, University of California San Francisco, San Francisco, California, USA.
Obesity (Silver Spring). 2023 Dec;31(12):2947-2959. doi: 10.1002/oby.23888. Epub 2023 Oct 5.
The National Health and Nutrition Examination Survey (NHANES) characterizes body composition representative of the US population using dual-energy x-ray absorptiometry (DXA) scans. These population-level trends of abdominal subcutaneous and visceral adipose tissue (SAT and VAT) are useful for identifying measures associated with increased disease risk. Recently, VAT and SAT data collected by Hologic DXA in NHANES were published online; however, there are known differences in the absolute calibration of DXA systems by make. The purpose of this study was to create reference tables suitable for calculating z scores and percentile values for GE HealthCare (GEHC) DXA systems.
DXA scans were acquired on participants aged 8 to 59 years using Hologic systems. DXA measures were converted to GEHC and described using the least median squares curve fitting method in pediatrics (aged <20 years) and adults (aged 20-59 years).
A total of 11,972 adults and 7298 pediatrics were included for this analysis. Adult and pediatric curves were generated by sex and by ethnicity (non-Hispanic White, non-Hispanic Black, Hispanic, Asian, Other) and were derived as a function of age.
These results show the ability to generate VAT and SAT reference data for GEHC systems using Hologic DXA data representative of the US youth and adult population.
国家健康和营养检查调查（NHANES）使用双能 X 射线吸收法（DXA）扫描来描述具有代表性的人体成分。这些腹部皮下和内脏脂肪组织（SAT 和 VAT）的人群水平趋势对于确定与疾病风险增加相关的措施很有用。最近，NHANES 中霍洛迪克斯纳（Hologic DXA）收集的 VAT 和 SAT 数据已在线发布；然而，不同制造商的 DXA 系统在绝对校准方面存在已知差异。本研究的目的是创建适用于计算 GE 医疗保健（GEHC）DXA 系统 z 分数和百分位数值的参考表。
使用霍洛迪克斯纳系统对 8 至 59 岁的参与者进行 DXA 扫描。使用儿科（年龄<20 岁）和成人（年龄 20-59 岁）中最小中位数平方曲线拟合方法将 DXA 测量值转换为 GEHC 并进行描述。
共有 11972 名成年人和 7298 名儿科患者纳入本分析。成人和儿科曲线按性别和种族（非西班牙裔白人、非西班牙裔黑人、西班牙裔、亚洲人、其他）生成，并作为年龄的函数得出。
这些结果表明，使用代表美国青年和成年人群体的霍洛迪克斯纳 DXA 数据，能够为 GEHC 系统生成 VAT 和 SAT 参考数据。
