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评价有/无富血小板纤维蛋白膜的非埋植式种植体周围软组织和牙槽骨变化:一项随机对照临床试验。

Evaluation of soft tissue and crestal bone changes around non-submerged implants with and without a platelet-rich fibrin membrane: A randomized controlled clinical trial.

机构信息

Department of Periodontology, Sibar Institute of Dental Sciences, Guntur, India.

Department of Prosthodontics, Sibar Institute of Dental Sciences, Guntur, India.

出版信息

Dent Med Probl. 2023 Jul-Sep;60(3):437-443. doi: 10.17219/dmp/150408.

DOI:10.17219/dmp/150408
PMID:37796049
Abstract

BACKGROUND

Platelet-rich fibrin (PRF) membranes are known to enhance wound healing after periodontal surgeries and dental implant procedures.

OBJECTIVES

The aim of the present study was to examine the effect of PRF on soft tissue healing and the crestal bone level (CBL) around non-submerged dental implants.

MATERIAL AND METHODS

A total of 40 patients, aged 20-60 years, with partially edentulous posterior mandibular sites were divided into 2 groups of 20 patients each: group I received non-submerged implants with a PRF membrane; and group II was treated with non-submerged implants alone. The examined parameters included the modified plaque index (mPI), the gingival index (GI), the width of keratinized tissue (WKT), the thickness of keratinized tissue (TKT), and CBL, assessed using digital intraoral periapical radiography (IOPA). All parameters were measured at baseline (immediately post-op), and at 3-month and 6-month follow-ups.

RESULTS

In comparison with baseline, statistically significant increases in WKT and TKT were observed in both groups at 3 and 6 months post-op (p < 0.05). Also, significant gains were noted in group I vs. group II (p < 0.05). The CBL increased significantly in both groups at 3 and 6 months post-op (p < 0.05), with no remarkable differences from 3 to 6 months. A decreased CBL was observed in group I vs. group II at the 3- and 6-month intervals (p < 0.05).

CONCLUSIONS

The PRF membrane enhances peri-implant tissue wound healing, with gains in soft tissue width and thickness around non-submerged implants.

摘要

背景

富血小板纤维蛋白(PRF)膜已被证实可促进牙周手术后和牙种植手术的伤口愈合。

目的

本研究旨在观察 PRF 对非潜入式牙种植体周围软组织愈合和牙槽嵴顶(CBL)水平的影响。

材料和方法

共纳入 40 名年龄在 20-60 岁之间、下颌后牙部分缺牙的患者,将其分为两组,每组 20 名患者:I 组接受非潜入式种植体加 PRF 膜治疗;II 组仅接受非潜入式种植体治疗。检查参数包括改良菌斑指数(mPI)、牙龈指数(GI)、角化组织宽度(WKT)、角化组织厚度(TKT)和 CBL,使用数字化口腔根尖片(IOPA)评估。所有参数均在基线(术后即刻)、术后 3 个月和 6 个月进行测量。

结果

与基线相比,两组患者在术后 3 个月和 6 个月时 WKT 和 TKT 均显著增加(p < 0.05)。同时,I 组与 II 组相比,WKT 和 TKT 均有显著增加(p < 0.05)。两组患者在术后 3 个月和 6 个月时 CBL 均显著增加(p < 0.05),但 3 个月和 6 个月之间无明显差异。I 组与 II 组相比,在术后 3 个月和 6 个月时 CBL 均有显著下降(p < 0.05)。

结论

PRF 膜可增强非潜入式种植体周围组织的伤口愈合,增加非潜入式种植体周围软组织的宽度和厚度。

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