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基于放射变色薄膜的新型二维剂量测定光机电传感器。

New opto-electro-mechanical sensor for two-dimensions dosimetry based on radiochromic films.

作者信息

Mena S, Karkour N, Alaphilippe V, Botero J P, Jiménez M, Linget D, Gibelin L, Le Ven V, Marquet A, Mellouh S, Josson E, Benassou W, Muñoz-Berbel X, Guirado G, Guardiola C

机构信息

Departament de Química, Universitat Autònoma de Barcelona, 08193, Bellaterra, Barcelona, Spain.

Instituto de Microelectrónica de Barcelona, (IMB-CNM, CSIC), 08193, Bellaterra, Spain.

出版信息

Sci Rep. 2023 Oct 5;13(1):16787. doi: 10.1038/s41598-023-43387-1.

Abstract

This work presents the validation of a new Opto‒Electro-Mechanical (MOEM) system consisting of a matrix of photodetectors for two-dimensional dosimetry evaluation with radiochromic films. The proposed system is based on a 5 × 10 matrix of photodetectors controlled by both in-house electronic circuit and graphical user interface, which enables optical measurements directly. We present the first tests performed in an X-ray machine and Cs source with that array by using Gafchromic EBT3 films. We obtained similar results than with a standard method (e.g. flat-bed scanner). Results were compared with Monte Carlo simulations and very good agreement was found. Results show the feasibility of using this system for dose evaluations. To the best of our knowledge, this is the first MOEM sensor for radiotherapy. Further developments are ongoing to create an advanced 16 × 16 LDRs system covering 1.6 cm × 1.6 cm with a 1 mm of spatial resolution. We point to develop a portable dosimetry tool delivering dose maps in real time to improve the clinical application of radiochromic films.

摘要

这项工作展示了一种新型光机电(MOEM)系统的验证情况,该系统由用于通过放射变色薄膜进行二维剂量测定评估的光电探测器矩阵组成。所提出的系统基于一个由内部电子电路和图形用户界面控制的5×10光电探测器矩阵,这使得能够直接进行光学测量。我们展示了首次使用该阵列通过Gafchromic EBT3薄膜在X射线机和铯源中进行的测试。我们获得了与标准方法(如平板扫描仪)相似的结果。将结果与蒙特卡罗模拟进行了比较,发现吻合度很高。结果表明使用该系统进行剂量评估是可行的。据我们所知,这是首款用于放射治疗的MOEM传感器。正在进行进一步开发,以创建一个先进的16×16低剂量率探测器(LDR)系统,覆盖面积为1.6厘米×1.6厘米,空间分辨率为1毫米。我们旨在开发一种便携式剂量测定工具,实时提供剂量图,以改善放射变色薄膜的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7178/10556105/372e426a6a24/41598_2023_43387_Fig1_HTML.jpg

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