该突变的基因定位。

Genetic mapping of the mutation in .

作者信息

Cordes Chloe N, Gouge Melissa M, Morgan Hannah, Porter Carah, Siders Jamie, Bacab Erica, Barin Briana, Becerra Ixel A, Castillo Jose, Church Jared, Condo-Hicks Shaunacee, Conroy Kattleya J, Curbelo-Navarro Isbel, DePrest Benjamin J, Eady Adrienne, Edmead TyMahni, Farouk Verena, Flores-Torres Angelica, Girmai Michael, Gutierrez Navarro Cynthia I, Guzman Stan, Harris Alexis B, Healy Karin, Jaafar Alina, Khadr Abraham, Kiboi Melissa N, Korte Stephanie N, Lopez Celia, Mahdi Hyder, Mendoza Avalos Jennifer, Miranda Kathy, Patel Dipti, Lopez Celia, Mahdi Hyder, Mendoza Avalos Jennifer, Miranda Kathy, Patel Dipti, Patel Rishi, Pechulis Sydney, Plachta Victoria, Rhodes Kamryn, Sandoval Andrea M, Thomas Caila, Valadez-Mendoza Joselyn A, Vora Hannah, Yousif Jonathan, Bieser Kayla L, Kagey Jacob D

机构信息

Ohio Northern University, Ada, OH, USA.

Nevada State University, Henderson, NV, USA.

出版信息

MicroPubl Biol. 2023 Sep 18;2023. doi: 10.17912/micropub.biology.000783. eCollection 2023.

DOI:10.17912/micropub.biology.000783

PMID:37799208

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10550376/

Abstract

An EMS-based forward genetic screen was conducted in an apoptotic null background to identify genetic aberrations that contribute to regulation of cell growth in . The current work maps the genomic location of one of the identified mutants, . Genetic crosses conducted through the Fly-CURE consortium determined that the gene locus for the mutation is on chromosome 2R.

摘要

在凋亡缺失背景下进行了基于EMS的正向遗传学筛选，以鉴定有助于调控细胞生长的遗传畸变。当前的工作确定了其中一个已鉴定突变体的基因组位置。通过Fly-CURE联盟进行的遗传杂交确定，该突变的基因座位于2R染色体上。