Krishnan Suhasini, Das Siddharth Sankar, Mahanta Sanjana, Das Susmita, Skikic Ena
Department of Medical Education, Dubai Academic Health Corporation, Dubai, ARE.
Department of General Surgery, Dubai Hospital, Dubai, ARE.
Cureus. 2023 Sep 3;15(9):e44623. doi: 10.7759/cureus.44623. eCollection 2023 Sep.
Pantoprazole is a proton-pump inhibitor mainly used in treating various gastroesophageal disorders and frequently as prophylaxis for stress ulcers and gastrointestinal bleeding in most patients admitted for in-hospital management. Hypersensitivity reactions to this medication have been reported, although the exact incidence and prevalence are unknown. Further studies on proton-pump inhibitor allergic reactions should be conducted to enable physicians to safely select and prescribe an alternative type of medication within the same drug class, confidently avoiding the allergenic molecular compound that the patient reacted to previously. We present a case of a 35-year-old male postoperative bariatric patient with no significant allergy history who developed an allergic skin rash a week after being discharged on pantoprazole 40 mg. His rash was itchy and distributed mainly over the torso and lower limbs, without any additional respiratory or gastrointestinal symptoms.
泮托拉唑是一种质子泵抑制剂，主要用于治疗各种胃食管疾病，在大多数住院治疗的患者中常作为应激性溃疡和胃肠道出血的预防用药。虽然对这种药物的过敏反应已有报道，但确切的发病率和患病率尚不清楚。应进一步开展关于质子泵抑制剂过敏反应的研究，以便医生能够在同一药物类别中安全地选择和开具替代药物，自信地避免患者先前发生反应的致敏分子化合物。我们报告一例35岁男性肥胖症术后患者，该患者无明显过敏史，在出院后服用40毫克泮托拉唑一周后出现过敏性皮疹。他的皮疹伴有瘙痒，主要分布在躯干和下肢，无任何其他呼吸道或胃肠道症状。
