泮托拉唑所致过敏反应：2例病例报告
Anaphylactic reactions due to pantoprazole: case report of two cases.
作者信息
Gupta Pramendra Prasad, Bhandari Rabin, Mishra Deebya Raj, Agrawal Krishna Kumar, Bhandari Rupak, Jirel Sunil, Malla Gyanendra
机构信息
Department of General Practice and Emergency Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
Department of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal.
出版信息
Int Med Case Rep J. 2018 May 23;11:125-127. doi: 10.2147/IMCRJ.S153099. eCollection 2018.
BACKGROUND
Drug-induced hypersensitivity reaction is of great clinical significance in therapeutics. The objective of this reporting of two cases is to show that anaphylaxis reaction can occur with pantoprazole.
CASE SUMMARIES
A 38-year-old female reported to the emergency ward in a critical condition, with a history of periorbital edema, edema of the skin, pruritus, nausea, vomiting, and difficulty breathing 20 minutes after ingestion of a pantoprazole 40 mg tablet. A 32-year-old female reported to the emergency ward in a critical condition, with complaints of rashes all over the body, itching on the whole body, and swollen lips and eyes after ingestion of a pantoprazole 40 mg tablet.
CONCLUSION
It is necessary for all health care providers to know that pantoprazole can cause anaphylaxis, which is a life-threatening reaction, and to be cautious while prescribing it.
背景
药物性过敏反应在治疗学中具有重要的临床意义。报告这两例病例的目的是表明泮托拉唑可引发过敏反应。
病例摘要
一名38岁女性因病情危急被送往急诊病房，有在服用40毫克泮托拉唑片20分钟后出现眶周水肿、皮肤水肿、瘙痒、恶心、呕吐及呼吸困难的病史。一名32岁女性因病情危急被送往急诊病房，自述在服用40毫克泮托拉唑片后出现全身皮疹、全身瘙痒以及嘴唇和眼睛肿胀。
结论
所有医疗保健人员都有必要了解泮托拉唑可引发过敏反应，这是一种危及生命的反应，在开处方时应谨慎。
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