Britton M G, Empey D W, John G C, Hodder M, Hughes D T
Ann Allergy. 1979 May;42(5):330-2.
Two doses of triprolidine (2.5 mg t.i.d. and 1.25 mg t.i.d.) were compared with placebo in 32 patients suffering from allergic rhinitis. Triprolidine 2.5 mg t.i.d. was statistically significantly better than placebo (p less than 0.05) in reducing the symptoms of sneezing and eye irritation. Neither dose of triprolidine produced significant drowsiness during the second week of treatment.
在32例过敏性鼻炎患者中,将两剂曲普利啶(每日三次,每次2.5毫克和每日三次,每次1.25毫克)与安慰剂进行了比较。每日三次服用2.5毫克曲普利啶在减轻打喷嚏和眼部刺激症状方面在统计学上显著优于安慰剂(p小于0.05)。在治疗的第二周,两种剂量的曲普利啶均未产生明显的嗜睡症状。