Division of Gastrointestinal Surgery, Department of General Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Xiang, Chengdu, 610041, China.
Department of General Surgery, The Second Clinical Medical College, The Fifth People's Hospital Affiliated to Chengdu University of Traditional Chinese Medicine, Chengdu, 610041, China.
Obes Surg. 2023 Nov;33(11):3510-3516. doi: 10.1007/s11695-023-06863-1. Epub 2023 Oct 7.
Dumping syndrome (DS) is a shared but underappreciated complication after metabolic-bariatric surgery. The purpose of the study was to investigate the prevalence and intensity of symptoms suggestive of DS and their relationship with health-related quality of life (HRQOL) after laparoscopic sleeve gastrectomy (LSG).
A retrospective cohort study was performed for all patients with a history of sleeve gastrectomy between July 2017 and July 2022 in our center. Basial clinic statistics were gathered from electronic medical database, the prevalence and severity of DS were assessed by Dumping Symptom Rating Scale (DSRS), and HRQOL is collected through the Short Form Health Survey 36 (SF-36).
In total, 133 of 202 patients completed the questionnaire (response rate 65.8%). A total of 64.7% (N = 86) of participants were female, aged 34.0 (IQR 26.0-39.0) years at completion of the questionnaire, with a mean body mass index of 35.8 (IQR 31.4-40.5) kg/m2. The prevalence of symptoms suggestive of DS was 45.9% (N = 61), and the associated protective factor was the time between surgery and study. Compared with the patients without DS, patients with DS scored significantly worse on four of eight SF-36 subdomains.
Symptoms suggestive of early dumping syndrome after sleeve gastrectomy are common and are associated with a worse health-related quality of life, which deserves clinical attention. Additional counselling, education, and care are needed to mitigate the decline in quality of life caused by dumping symptoms.
倾倒综合征（DS）是代谢性减重手术后常见但未被充分认识的并发症。本研究旨在探讨腹腔镜袖状胃切除术（LSG）后提示 DS 的症状发生率和严重程度及其与健康相关生活质量（HRQOL）的关系。
本研究对 2017 年 7 月至 2022 年 7 月期间在我中心接受袖状胃切除术的所有患者进行了回顾性队列研究。基本临床统计数据来自电子病历数据库，通过倾倒症状评分量表（DSRS）评估 DS 的发生率和严重程度，通过健康调查简表 36（SF-36）评估 HRQOL。
共有 202 名患者中的 133 名完成了问卷调查（应答率为 65.8%）。完成问卷时，共有 64.7%（N=86）的参与者为女性，年龄为 34.0（IQR 26.0-39.0）岁，平均体重指数为 35.8（IQR 31.4-40.5）kg/m2。DS 症状发生率为 45.9%（N=61），手术与研究之间的时间是其保护因素。与无 DS 的患者相比，有 DS 的患者在 8 个 SF-36 子领域中的 4 个领域的评分显著更差。
LSG 后早期倾倒综合征的症状发生率较高，且与较差的 HRQOL 相关，值得临床关注。需要额外的咨询、教育和护理，以减轻倾倒症状引起的生活质量下降。
