Chen Z Y, Hu S Q, Liu D W, Zhang H Y, Guo G H, Mao Y G
Medical Center of Burn Plastic and Wound Repair, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi. 2023 Apr 20;39(4):391-395. doi: 10.3760/cma.j.cn501225-20220412-00134.
Mortality due to severe burns has always been at a high level. A large number of studies have shown that the rapid onset of infectious symptoms and rapid progression of severely burned patients are closely related to the occurrence of cytokine storm. However, in clinical practice, cytokine storm monitoring, early warning, and symptomatic treatment are still in exploratory stage. This article reviews the cytokine storm and its related cytokines, the mechanism, early warning, and treatment of cytokine storm induced by burn infection, aiming to provide clinical references for reducing infection and mortality in severely burned patients.
严重烧伤导致的死亡率一直处于较高水平。大量研究表明，严重烧伤患者感染症状的快速出现和病情的迅速进展与细胞因子风暴的发生密切相关。然而，在临床实践中，细胞因子风暴的监测、预警及对症治疗仍处于探索阶段。本文综述了细胞因子风暴及其相关细胞因子、烧伤感染诱导细胞因子风暴的机制、预警及治疗，旨在为降低严重烧伤患者的感染率和死亡率提供临床参考。
