Flandrois R, Grandmontagne M, Gerin H, Mayet M H, Jehl J L, Eyssette M
Eur J Appl Physiol Occup Physiol. 1986;55(6):604-9. doi: 10.1007/BF00423204.
To determine adaptation to prolonged exercise in paraplegics, maximal O2 uptake (VO2max) and lactate threshold (LT) were evaluated during an arm cranking exercise in nine patients (P) and nine able-bodied (AB) subjects. Mean VO2max averaged 25.1 and 31.6 ml X min-1 X kg-1 in P and AB groups respectively. VO2max in P was found to be directly related to the level of spinal injury: the higher the lesion the lower the uptake. Lactate threshold expressed as a percentage of VO2max was higher in P (59%) than in AB (43%), and close to that observed in arm-trained athletes. Since training has less effect on VO2max in paraplegics than in able-bodied subjects, attributable to a deficiency in the circulatory adaptation of paraplegics to exercise, the observed differences between AB and P in lactate threshold and submaximal exercise indicate that the possible effect of training in paraplegics is located at the level of intracellular chemistry, with a diminution in glycogenolysis (higher LT) and a higher rate of lipid utilization (lower RQ).
为了确定截瘫患者对长时间运动的适应性，对9名患者（P）和9名健全人（AB）进行了手摇曲柄运动，评估了他们的最大摄氧量（VO2max）和乳酸阈（LT）。P组和AB组的平均VO2max分别为25.1和31.6毫升·分钟-1·千克-1。发现P组的VO2max与脊髓损伤水平直接相关：损伤越高，摄氧量越低。以VO2max的百分比表示的乳酸阈在P组（59%）高于AB组（43%），且接近手臂训练运动员的水平。由于训练对截瘫患者VO2max的影响小于健全人，这归因于截瘫患者对运动的循环适应性不足，AB组和P组在乳酸阈和次最大运动方面的差异表明，训练对截瘫患者的可能影响位于细胞内化学水平，糖原分解减少（较高的LT）和脂质利用率较高（较低的呼吸商）。
