Kwentoh Ifeoma, Adelodun Anuoluwapo, Bortier Theophilus, Ogbovoh Daniel, Scott Earl
Internal Medicine, Columbia University College of Physicians and Surgeons, Harlem Hospital Center, New York, USA.
Internal Medicine, Columbia University College of Physicians and Surgeons, Harlem Hospital Center, New york, USA.
Cureus. 2023 Oct 6;15(10):e46597. doi: 10.7759/cureus.46597. eCollection 2023 Oct.
Herb-induced liver injury (HILI) is a global concern due to the uptrend in Complementary and Alternative Medicine (CAM). The authors add to the current literature by reporting a case of a 61-year-old man with recent travel to Haiti. His past medical history include hepatitis C virus treated in 2021 with a sustained virologic response (SVR). He presented with profound weakness and abnormal liver transaminases in the thousands. It was initially unclear what the etiology of the patient's hepatocellular necrosis was, however, the level of abnormality was most consistent with either toxic metabolic injury or vascular ischemic injury. We initiated N-acetylcysteine and vitamin K and had a positive outcome. Upon further questioning, he admitted to consuming an herbal product cleansing tea called "asowosi" in large quantities. We searched the botanical name of the extract and found the active ingredient was . The team utilized the updated Roussel Uclaf Causality Assessment Method (RUCAM), and the results demonstrated a highly probable relationship with .
由于补充和替代医学（CAM）的使用呈上升趋势，草药引起的肝损伤（HILI）已成为一个全球性问题。作者通过报告一例61岁近期去过海地的男性病例，为当前文献增添了内容。他的既往病史包括2021年接受过丙型肝炎病毒治疗并获得持续病毒学应答（SVR）。他出现了极度虚弱和转氨酶异常升高至数千的情况。最初尚不清楚该患者肝细胞坏死的病因，但异常程度最符合毒性代谢损伤或血管缺血性损伤。我们开始使用N - 乙酰半胱氨酸和维生素K，并取得了积极效果。经进一步询问，他承认大量饮用了一种名为“asowosi”的草药清洁茶。我们查找了提取物的植物学名，发现活性成分是 。该团队采用了更新后的鲁塞尔·乌克拉夫因果关系评估方法（RUCAM），结果显示与 有高度可能的关系。
