Stefoni S, Colì L, Feliciangeli G, Scolari M P, Bonomini V
Int J Artif Organs. 1986 Sep;9(5):297-300.
This paper reports the Authors' 8 year experience in the clinical use of charcoal hemoperfusion as a means to reduce the weekly time of treatment in chronic uremic patients. Two different programmes were applied. Programme A (34 patients) which involved substituting the 3 procedures per week of standard dialysis (4 hours duration each) by 2 procedures of combined hemodialysis and hemoperfusion, again of 4 hours duration each. Programme B (18 patients) which involved substituting the 3 procedures per week of 4 hours duration by 3 procedures of 3 hours each, 2 of combined hemodialysis and hemoperfusion, 1 of conventional dialysis. The net weekly reduction was 33% for Programme A and 25% for Programme B. The efficacy of the two Programmes was evaluated by clinical, hematochemical, nutritional and instrumental parameters.
本文报告了作者在将活性炭血液灌流作为减少慢性尿毒症患者每周治疗时间的一种手段的临床应用方面的8年经验。应用了两种不同的方案。方案A(34例患者),即每周将3次标准透析(每次4小时)替换为2次血液透析和血液灌流联合治疗,每次同样为4小时。方案B(18例患者),即每周将3次每次4小时的治疗替换为3次每次3小时的治疗,其中2次为血液透析和血液灌流联合治疗,1次为常规透析。方案A每周净减少33%,方案B每周净减少25%。通过临床、血液化学、营养和仪器参数对两种方案的疗效进行了评估。