Zareshahrabadi Zahra, Saharkhiz Mohammad Jamal, Izadpanah Maryam, Iraji Aida, Emaminia Maryam, Motealeh Maryam, Khodadadi Hossein, Zomorodian Kamiar
Basic Sciences in Infectious Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Evid Based Complement Alternat Med. 2023 Oct 3;2023:3423440. doi: 10.1155/2023/3423440. eCollection 2023.
is a plant of the family that grows in different parts of the world and the vicinity of seasonal rivers in Iran.
The chemical composition of the essential oils was distilled and evaluated using gas chromatography/mass spectrometry. The antifungal activity of the essential oils against the fungal strains was analyzed by broth microdilution methods as suggested by the Clinical and Laboratory Standards Institute. Furthermore, the antibiofilm activity of the essential oils was assessed using the XTT reduction assay.
Based on GC/MS analysis, the major components of the essential oils were -pinene, -terpinyl acetate, limonene, and (E)-caryophyllene. The growth of tested yeasts was inhibited at concentrations ranging from 2 to 64 l/mL. fruit essential oil was the most effective in inhibiting yeast growth. Moreover, the essential oils exhibited antifungal activity against filamentous fungi strains. Additionally, the biofilm formation of was inhibited by the leaf, flower, and fruit of the essential oils.
Considering the significant antifungal activities of these essential oils, they can be considered a potential source for formulating novel agents to control fungal infections.
是一种生长在世界不同地区以及伊朗季节性河流附近的植物。
通过气相色谱/质谱联用仪对该植物精油的化学成分进行蒸馏和评估。按照临床和实验室标准协会的建议，采用肉汤微量稀释法分析该精油对真菌菌株的抗真菌活性。此外，使用XTT还原法评估该精油的抗生物膜活性。
基于气相色谱/质谱分析，该精油的主要成分是α-蒎烯、乙酸α-萜品酯、柠檬烯和（E）-石竹烯。受试酵母在浓度为2至64μL/mL范围内的生长受到抑制。该植物果实精油在抑制酵母生长方面最为有效。此外，该精油对丝状真菌菌株也表现出抗真菌活性。另外，该植物的叶、花和果实精油可抑制生物膜的形成。
鉴于这些精油具有显著的抗真菌活性，它们可被视为开发新型抗真菌感染制剂的潜在来源。
