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姑息治疗中的临床试验：需要认真反思。

Clinical Trials in Palliative Care: Need for Serious Reckoning.

机构信息

All India Institute of Medical Sciences, Deoghar, India.

出版信息

JCO Glob Oncol. 2023 Sep;9:e2300181. doi: 10.1200/GO.23.00181.

DOI:10.1200/GO.23.00181
PMID:37824801
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10664857/
Abstract

We explore five crucial insights on Clinical Trials in Palliative care. From setting impactful priorities to ethical funding, we delve into the heart of informed patient care and discover how 'Ground Shots' can drive meaningful changes and why collaborati

摘要

我们探讨了关于姑息治疗临床试验的五个关键见解。从设定有影响力的优先事项到伦理资助，我们深入探讨了知情患者护理的核心，发现“实地研究”如何能够带来有意义的变革，以及为什么合作至关重要。

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本文引用的文献

1
Tolerating bad health research: the continuing scandal.容忍不良健康研究：持续的丑闻。
Trials. 2022 Jun 2;23(1):458. doi: 10.1186/s13063-022-06415-5.
2
Cancer Groundshot: Building a Robust Cancer Control Platform in Addition To Launching the Cancer Moonshot.癌症全面防控：除了启动癌症登月计划，还要构建强大的癌症防控平台。
Am Soc Clin Oncol Educ Book. 2022 Apr;42:1-16. doi: 10.1200/EDBK_359521.
3
Cancer treatments should benefit patients: a common-sense revolution in oncology.癌症治疗应使患者受益：肿瘤学的一场常识性变革。
Nat Med. 2022 Apr;28(4):617-620. doi: 10.1038/s41591-021-01662-6.
4
Recovery trial lead launches organisation to cut costs of clinical trials.康复试验负责人成立组织以削减临床试验成本。
BMJ. 2022 Jan 24;376:o203. doi: 10.1136/bmj.o203.
5
Methodology over metrics: current scientific standards are a disservice to patients and society.方法重于指标：当前的科学标准对患者和社会不利。
J Clin Epidemiol. 2021 Oct;138:219-226. doi: 10.1016/j.jclinepi.2021.05.018. Epub 2021 May 30.
6
An Analysis of Contemporary Oncology Randomized Clinical Trials From Low/Middle-Income vs High-Income Countries.低收入和中等收入国家与高收入国家当代肿瘤随机临床试验分析。
JAMA Oncol. 2021 Mar 1;7(3):379-385. doi: 10.1001/jamaoncol.2020.7478.
7
International palliative care research priorities: A systematic review.国际姑息治疗研究重点：系统评价。
BMC Palliat Care. 2020 Feb 3;19(1):16. doi: 10.1186/s12904-020-0520-8.
8
Barriers for conducting clinical trials in developing countries- a systematic review.发展中国家开展临床试验的障碍：系统评价。
Int J Equity Health. 2018 Mar 22;17(1):37. doi: 10.1186/s12939-018-0748-6.
9
Cancer groundshot: going global before going to the moon.癌症地面计划：在登月之前走向全球。
Lancet Oncol. 2018 Mar;19(3):288-290. doi: 10.1016/S1470-2045(18)30076-7.
10
Magnitude of Clinical Benefit of Cancer Drugs Approved by the US Food and Drug Administration.美国食品和药物管理局批准的癌症药物的临床获益幅度。
J Natl Cancer Inst. 2018 May 1;110(5):486-492. doi: 10.1093/jnci/djx232.