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癌症全面防控:除了启动癌症登月计划,还要构建强大的癌症防控平台。

Cancer Groundshot: Building a Robust Cancer Control Platform in Addition To Launching the Cancer Moonshot.

机构信息

Breast Surgical Oncology, Aga Khan University, Nairobi, Kenya.

Department of Oncology, Queen's University, Kingston, Ontario, Canada.

出版信息

Am Soc Clin Oncol Educ Book. 2022 Apr;42:1-16. doi: 10.1200/EDBK_359521.

Abstract

Cancer Groundshot is a philosophy that calls for prioritization of strategies in global cancer control. The underlying principle of Cancer Groundshot is that one must ensure access to interventions that are already proven to work before focusing on the development of new interventions. In this article, we discuss the philosophy of Cancer Groundshot as it pertains to priorities in cancer care and research in low- and middle-income countries and the utility of technology in addressing global cancer disparities; we also address disparities seen in high-income countries. The oncology community needs to realign our priorities and focus on improving access to high-value cancer control strategies, rather than allocating resources primarily to the development of technologies that provide only marginal gains at a high cost. There are several "low-hanging fruit" actions that will improve access to quality cancer care in low- and middle-income countries and in high-income countries. Worldwide, cancer morbidity and mortality can be averted by implementing highly effective, low-cost interventions that are already known to work, rather than investing in the development of resource-intensive interventions to which most patients will not have access (i.e., we can use Cancer Groundshot to first save more lives before we focus on the "moonshots").

摘要

癌症狙击是一种倡导在全球癌症控制中优先考虑策略的理念。癌症狙击的基本原则是,在关注新干预措施的开发之前,必须确保能够获得已经证明有效的干预措施。在本文中,我们将讨论癌症狙击的理念,以及它与中低收入国家癌症护理和研究的优先事项的关系,以及技术在解决全球癌症差距方面的应用;我们还将讨论高收入国家存在的差距。肿瘤学界需要重新调整我们的优先事项,专注于改善获得高价值癌症控制策略的机会,而不是主要将资源分配给提供边际收益但成本高昂的技术的开发。有一些“低挂果实”的行动可以改善中低收入国家和高收入国家获得高质量癌症护理的机会。在全球范围内,可以通过实施已经证明有效的、低成本的干预措施来避免癌症发病率和死亡率,而不是投资于资源密集型干预措施的开发,因为大多数患者无法获得这些干预措施(即,我们可以先用癌症狙击来挽救更多生命,然后再关注“登月计划”)。

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